Cyanine5.5 amine

Cat. # Quantity Price Lead time
170C0 1 mg $125 in stock
270C0 5 mg $260 in stock
470C0 25 mg $510 in stock
570C0 50 mg $895 in stock
670C0 100 mg $1490 in stock
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Cyanine5.5 (Cy5.5® analog) amine derivative. The dye contains a free amine group which can be conjugated with a variety of functionalities, including NHS esters, and epoxides.

Cyanine5.5 is a far red dye which works fine for live organism imaging, and applications requiring low fluorescence background.

Cy5.5 absorbance and emission spectra

Cy5.5 absorbance and emission spectra

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General properties

Appearance: dark blue powder
Molecular weight: 753.88
CAS number: 2097714-44-6 (without anion), 2097714-45-7 (chloride)
Molecular formula: C46H58Cl2N4O
Solubility: practically insoluble in water (< 2 uM), good in polar organic solvents (DMF, DMSO, alcohols)
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 684
ε, L⋅mol−1⋅cm−1: 198000
Emission maximum, nm: 710
Fluorescence quantum yield: 0.2
CF260: 0.07
CF280: 0.03

Product citations

  1. Schvartzman, C.; Ibarboure, E.; Martin, A.; Garanger, E.; Mutschler, A.; Lecommandoux, S. Protocells Featuring Membrane-Bound and Dynamic Membraneless Organelles. Biomacromolecules, 2024, 25(7), 4087–4094. doi: 10.1021/acs.biomac.4c00200
  2. ten Hove, M.; Smyris, A.; Booijink, R.; Wachsmuth, L.; Hansen, U.; Alic, L.; Faber, C.; Hӧltke, C.; Bansal, R. Engineered SPIONs functionalized with endothelin a receptor antagonist ameliorate liver fibrosis by inhibiting hepatic stellate cell activation. Bioactive Materials, 2024, 39, 406-426. doi: 10.1016/j.bioactmat.2024.05.034
  3. Ayala-Orozco, C.; Li, G.; Li, B.; Vardanyan, V.; Kolomeisky, A. B.; Tour, J. M. How to Build Plasmon-Driven Molecular Jackhammers That Disassemble Cell Membranes and Cytoskeletons in Cancer. Advanced Materials, 2024, 36(14), 2309910. doi: 10.1002/adma.202309910
  4. Grosmanová, E.; Pola, R.; Filipová, M.; Henry, M.; Coll, J.‐L.; Etrych, T. Novel strategies for enhanced fluorescence visualization of glioblastoma tumors based on HPMA copolymers conjugated with tumor targeting and/or cell‐penetrating peptides. VIEW, 2024, 5(3), 20230116. doi: 10.1002/viw.20230116
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