Cyanine5.5 amine

Cat. # Quantity Price Lead time
170C0 1 mg $110.00 in stock
270C0 5 mg $210.00 in stock
470C0 25 mg $410.00 in stock
570C0 50 mg $695.00 in stock
670C0 100 mg $1190.00 in stock

Cyanine5.5 (Cy5.5® analog) amine derivative. The dye contains a free amine group which can be conjugated with a variety of functionalities, including NHS esters, and epoxides.

Cyanine5.5 is a far red dye which works fine for live organism imaging, and applications requiring low fluorescence background.

Cy5.5 absorbance and emission spectra

Cy5.5 absorbance and emission spectra

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General properties

Appearance: dark blue powder
Molecular weight: 753.88
CAS number: 2097714-44-6 (without anion), 2097714-45-7 (chloride)
Molecular formula: C46H58Cl2N4O
IUPAC name: 1H-​Benz[e]​indolium, 2-​[5-​[3-​[6-​[(6-​aminohexyl)​amino]​-​6-​oxohexyl]​-​1,​3-​dihydro-​1,​1-​dimethyl-​2H-​benz[e]​indol-​2-​ylidene]​-​1,​3-​pentadien-​1-​yl]​-​1,​1,​3-​trimethyl-
Solubility: practically insoluble in water (< 2 uM), good in polar organic solvents (DMF, DMSO, alcohols)
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.
MSDS: Download
Product specifications

Spectral properties

Excitation maximum, nm: 684
ε, L⋅mol−1⋅cm−1: 198000
Emission maximum, nm: 710
Fluorescence quantum yield: 0.2
CF260: 0.07
CF280: 0.03

Product citations

  1. Park, D.J.; Yun, W.S.; Kim, W.C.; Park, J.-E.; Lee, S.H.; Ha, S.; Choi, J.S.; Key, J.; Seo, Y.J. Improvement of stem cell-derived exosome release efficiency by surface modified nanoparticles. Research Square, preprint. doi: 10.21203/rs.3.rs-42143/v1
  2. Saito, E.; Gurczynski, S.J.; Kramer, K.R.; Wilke, C.A.; Miller, S.D.; Moore, B.B.; Shea, L.D. Modulating lung immune cells by pulmonary delivery of antigen-specific nanoparticles to treat autoimmune disease. Science Advances, 2020, 6(42), eabc9317. doi: 10.1126/sciadv.abc9317
  3. Xie, H.; Zhu, H.; Zhou, K.; Wan, J.; Zhang, L.; Yang, Z.; Zhou, L.; Chen, X.; Xu, X.; Zheng, S.; Wang, H. Target-oriented delivery of self-assembled immunosuppressant cocktails prolongs allogeneic orthotopic liver transplant survival. Journal of Controlled Release, 2020, 328, 237–250. doi: 10.1016/j.jconrel.2020.08.043
  4. Lee, S.H.; Park, D.J.; Yun, W.S.; Park, J.-E.; Choi, J.S.; Key, J.; Seo, Y.J. Endocytic trafficking of polymeric clustered superparamagnetic iron oxide nanoparticles in mesenchymal stem cells. Journal of Controlled Release, 2020, 326, 408–418. doi: 10.1016/j.jconrel.2020.07.032
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