Cyanine5.5 amine

Cat. # Quantity Price Lead time
170C0 1 mg $110.00 in stock
270C0 5 mg $210.00 in stock
470C0 25 mg $410.00 in stock
570C0 50 mg $695.00 in stock
670C0 100 mg $1190.00 in stock

Cyanine5.5 (Cy5.5® analog) amine derivative. The dye contains a free amine group which can be conjugated with a variety of functionalities, including NHS esters, and epoxides.

Cyanine5.5 is a far red dye which works fine for live organism imaging, and applications requiring low fluorescence background.

Cy5.5 absorbance and emission spectra

Cy5.5 absorbance and emission spectra

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Amine reactive NHS ester of NIR fluorescent dye Cyanine7.5.
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Cyanine5 amine

Cyanine5 amine functionalized dye for the coupling with activated esters and epoxides.
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General properties

Appearance: dark blue powder
Molecular weight: 753.88
CAS number: 2097714-44-6 (without anion), 2097714-45-7 (chloride)
Molecular formula: C46H58Cl2N4O
IUPAC name: CAS Registry Number 2097714-45-7 (Component: 2097714-44-6) ~1~1 C46 H57 N4 O . Cl H . Cl 1H-​Benz[e]​indolium, 2-​[5-​[3-​[6-​[(6-​aminohexyl)​amino]​-​6-​oxohexyl]​-​1,​3-​dihydro-​1,​1-​dimethyl-​2H-​benz[e]​indol-​2-​ylidene]​-​1,​3-​pentadien-​1-​yl]​-​1,​1,​3-​trimethyl-
Solubility: moderate solubility in water, good in polar organic solvents (DMF, DMSO, alcohols)
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.
MSDS: Download
Product specifications

Spectral properties

Excitation maximum, nm: 684
ε, L⋅mol−1⋅cm−1: 209000
Emission maximum, nm: 710
Fluorescence quantum yield: 0.2
CF260: 0.07
CF280: 0.03

Product citations

  1. Saito, E.; Kuo, R.; Pearson, R.M.; Gohel, N.; Cheung, B.; King, N.J.C.; Miller, S.D.; Shea, L.D. Designing drug-free biodegradable nanoparticles to modulate inflammatory monocytes and neutrophils for ameliorating inflammation. Journal of Controlled Release, in press. doi: 10.1016/j.jconrel.2019.02.025
  2. Shim, K.-S.; Kim, H.-J.; Kim, S.E.; Park, K. Simple surface biofunctionalization of biphasic calcium phosphates for improving osteogenic activity and bone tissue regeneration. Journal of Industrial and Engineering Chemistry, 2018, 68, 228–228. doi: 10.1016/j.jiec.2018.07.048
  3. Qiao, R.; Esser, L.; Fu, C.; Zhang, C.; Hu, J.; Ramírez-García, P.; Li, Y.; Quinn, J.F.; Whittaker, M.R.; Whittaker, A.K.; Davis, T.P. Bioconjugation and Fluorescence Labelling of Iron Oxide Nanoparticles Grafted with Bromomaleimide-terminal Polymers. Biomacromolecules, 2018, 19(11), 4423–4429. doi: 10.1021/acs.biomac.8b01282
  4. Lee, S.Y.; Ko, S.-H.; Shim, J.-S.; Kim, D.-D.; Cho, H.-J. Tumor Targeting and Lipid Rafts Disrupting Hyaluronic Acid-Cyclodextrin-Based Nanoassembled Structure for Cancer Therapy. ACS Applied Materials & Interfaces, 2018, 10(43), 36628–36640. doi: 10.1021/acsami.8b08243
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