Cyanine5.5 amine
| Cat. # | Quantity | Price | Lead time | Buy this product |
|---|---|---|---|---|
| 170C0 | 1 mg | $110.00 | in stock | |
| 270C0 | 5 mg | $210.00 | in stock | |
| 470C0 | 25 mg |
$410.00
|
in stock | |
| 570C0 | 50 mg |
$695.00
|
in stock | |
| 670C0 | 100 mg |
$1190.00
|
in stock |
Cyanine5.5 (Cy5.5® analog) amine derivative. The dye contains a free amine group which can be conjugated with a variety of functionalities, including NHS esters, and epoxides.
Cyanine5.5 is a far red dye which works fine for live organism imaging, and applications requiring low fluorescence background.
Cy5.5 absorbance and emission spectra
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Catalyst for bioconjugate synthesis by Click Chemistry.Sulfo-Cyanine5.5 NHS ester
Water soluble, sulfonated, far-red sulfo-Cyanine5.5 dye in the form of NHS ester.General properties
| Appearance: | dark blue powder |
| Molecular weight: | 753.88 |
| CAS number: | 2097714-44-6 (without anion), 2097714-45-7 (chloride) |
| Molecular formula: | C46H58Cl2N4O |
| IUPAC name: | 1H-Benz[e]indolium, 2-[5-[3-[6-[(6-aminohexyl)amino]-6-oxohexyl]-1,3-dihydro-1,1-dimethyl-2H-benz[e]indol-2-ylidene]-1,3-pentadien-1-yl]-1,1,3-trimethyl- |
| Solubility: | practically insoluble in water (< 2 uM), good in polar organic solvents (DMF, DMSO, alcohols) |
| Quality control: | NMR 1H, HPLC-MS (95%) |
| Storage conditions: | Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate. |
| MSDS: | Download |
| Product specifications |
Spectral properties
| Excitation maximum, nm: | 684 |
| ε, L⋅mol−1⋅cm−1: | 198000 |
| Emission maximum, nm: | 710 |
| Fluorescence quantum yield: | 0.2 |
| CF260: | 0.07 |
| CF280: | 0.03 |
Product citations
- Zhang, E.; Zhukova, V.; Semyonkin, A.; Osipova, N.; Malinovskaya, Y.; Maksimenko, O.; Chernikov, V.; Sokolov, M.; Grigartzik, L.; Sabel, B.A.; Gelperina, S.; Henrich-Noack, P. Release kinetics of fluorescent dyes from PLGA nanoparticles in retinal blood vessels: in vivo monitoring and ex vivo localization. European Journal of Pharmaceutics and Biopharmaceutics, 2020, 150, 131–142. doi: 10.1016/j.ejpb.2020.03.006
- Maksimenko, O.; Malinovskaya, Y.; Shipulo, E.; Osipova, N.; Razzhivina, V.; Arantseva, D.; Yarovaya, O.; Mostovaya, U.; Khalansky, A.; Fedoseeva, V.; Alekseeva, A.; Vanchugova, L.; Gorshkova, M.; Kovalenko, E.; Balabanyan, V.; Melnikov, P.; Baklaushev, V.; Chekhonin, V.; Kreuter, J.; Gelperina, S. Doxorubicin-loaded PLGA nanoparticles for the chemotherapy of glioblastomas: Towards the pharmaceutical development. International Journal of Pharmaceutics, 2019, 572, 118733. doi: 10.1016/j.ijpharm.2019.118733
- Park, J.; Zhang, Y.; Saito, E.; Gurczynski, S.J.; Moore, B.B.; Cummings, B.J.; Anderson, A.J.; Shea, L.D. Intravascular innate immune cells reprogrammed via intravenous nanoparticles to promote functional recovery after spinal cord injury. Proceedings of the National Academy of Sciences of the U.S.A., 2019, 116(30), 14947–14954. doi: 10.1073/pnas.1820276116
- Saito, E.; Kuo, R.; Kramer, K.R.; Gohel, N.; Giles, D.A.; Moore, B.B.; Miller, S.D.; Shea, L.D. Design of biodegradable nanoparticles to modulate phenotypes of antigen presenting cells for antigen-specific treatment of autoimmune disease. Biomaterials, 2019, 222, 119432. doi: 10.1016/j.biomaterials.2019.119432
Cy® is a trademark of GE Healthcare.
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