AMCA carboxylic acid

AMCA Carboxylic acids

Cat. #	Quantity	Price	Lead time
3357-25mg	25 mg	$45	in stock
3357-100mg	100 mg	$95	in stock
3357-1g	1 g	$490	in stock

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AMCA (aminomethylcoumarin acetate) is one of the brightest blue fluorescent dyes. This fluorophore has a relatively large Stoke’s shift, high resistance to photobleaching, and pH-independent fluorescence from pH 4 to 10. AMCA is a widely used fluorophore for multiple-color labeling due to its minimal fluorescence overlap with green- and longer wavelength-emitting fluorescent dyes.

AMCA carboxylic acid is a non-reactive form of AMCA dye that can be used as a reference standard in experiments involving AMCA dye conjugates. Besides, the carboxylic group can react with hydrazines, hydroxylamines, and amines using carbodiimides such as EDAC.

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Absorption and emission spectra of AMCA

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General properties

Appearance:	off-white solid
Molecular weight:	233.22
Molecular formula:	C₁₂H₁₁NO₄
Solubility:	good in DMSO, DMF
Quality control:	NMR ¹H and HPLC-MS (95+%)
Storage conditions:	24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Desiccate.
MSDS:	Download
	Product specifications

Spectral properties

Excitation/absorption maximum, nm:	348
ε, L⋅mol⁻¹⋅cm⁻¹:	17400
Emission maximum, nm:	435
Fluorescence quantum yield:	0.91
CF₂₆₀:	0.16
CF₂₈₀:	0.13

This Product is offered and sold for research purposes only. It has not been tested for safety and efficacy in food, drug, medical device, cosmetic, commercial or any other use. Supply does not express or imply authorization to use for any other purpose, including, without limitation, in vitro diagnostic purposes, in the manufacture of food or pharmaceutical products, in medical devices or in cosmetic products.