sulfo-Cyanine7.5 carboxylic acid

Cat. # Quantity Price Lead time
16390 1 mg $125 in stock
26390 5 mg $325 in stock
46390 25 mg $850 in stock
56390 50 mg $1490 in stock
66390 100 mg $1990 in stock
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sulfo-Cyanine7.5 is a water-soluble, near-infrared fluorescent dye. The structure of the dye is similar to indocyanine green (ICG), but it contains a rigid trimethine linker increasing its fluorescence quantum yield.

This fluorophore is useful for near-infrared imaging. sulfo-Cyanine7.5 carboxylic acid contains a free carboxy group.

Absorption and emission spectra of sulfo-Cyanine7.5

Absorption and emission spectra of sulfo-Cyanine7.5

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Indocyanine Green (ICG)

Water-soluble and pH-insensitive fluorescent dye widely used in imaging and flow cytometry.

General properties

Appearance: dark green solid
Molecular weight: 1083.41
Molecular formula: C45H45K3N2O14S4
Solubility: good in water, DMF, DMSO
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 778
ε, L⋅mol−1⋅cm−1: 222000
Emission maximum, nm: 797
Fluorescence quantum yield: 0.21
CF260: 0.09
CF280: 0.09

Product citations

  1. Goto, Y.; Ando, K.; Takakura, H.; Nakajima, K.; Kobayashi, M.; Inanami, O.; Taketsugu, T.; Ogawa, M. Development of a red-shifted photosensitizer for near-infrared photoimmunotherapy of cancer. Journal of Photochemistry and Photobiology, 2024, 20, 100230. doi: 10.1016/j.jpap.2024.100230
  2. So, I.-S.; Kang, J.H.; Hong, J.W.; Sung, S.; Hasan, A.F.; Sa, K.H.; Han, S.W.; Kim, I.S.; Kang, Y.M. A novel apoptosis probe, cyclic ApoPep-1, for in vivo imaging with multimodal applications in chronic inflammatory arthritis. Apoptosis, 2021, 26(3–4), 209–218. doi: 10.1007/s10495-021-01659-z
  3. Matoori, S.; Mooney, D.J. Near-Infrared Fluorescence Hydrogen Peroxide Assay for Versatile Metabolite Biosensing in Whole Blood. Small, 2020, 16(20), 2000369. doi: 10.1002/smll.202000369
  4. Shi, F.; Li, M.; Wu, S.; Yang, F.; Di, W.; Pan, M.; Zhao, F.; Luo, S.; Gu, N.; Dou, J. Enhancing the Anti-Multiple Myeloma Efficiency in a Cancer Stem Cell Xenograft Model by Conjugating the ABCG2 Antibody with Microbubbles for a Targeted Delivery of Ultrasound Mediated Epirubicin. Biochemical Pharmacology, 2017, 132, 18–28. doi: 10.1016/j.bcp.2017.02.014
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