ROX azide, 5-isomer
| Cat. # | Quantity | Price | Lead time | Buy this product |
|---|---|---|---|---|
| A1230 | 1 mg | $110 | in stock | |
| B1230 | 5 mg | $165 | in stock | |
| C1230 | 10 mg | $210 | in stock | |
| D1230 | 25 mg | $299 | in stock | |
| E1230 | 50 mg |
$495
|
in stock |
ROX azide is an alkyne-reactive derivative of ROX (Rhodamine X, Rhodamine 101) dye. ROX is a red-emitting fluorophore possessing high brightness and fluorescence quantum yield. This reagent is a pure 5-isomer. It is used for labeling alkyne and cycloalkyne-containing biomolecules via copper-catalyzed and copper-free click chemistry reactions.
Absorption and emission spectra of ROX dye
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A catalyst for click reaction. A stable copper(II) complex which must be converted to monovalent copper(I) in situ using reducing agents. The complex can be used to prepare a reaction buffer of any composition.Alkyne CPG 1000A
Controlled pore glass solid support for DNA/RNA synthesis with alkyne modification (pore size 1000 Å) for synthesizing long-modified oligonucleotides with 3'-alkyne modification.sulfo-Cyanine5.5 azide
sulfo-Cyanine5.5 azide is a derivative of water-soluble far-red emitting fluorescent cyanine dye. The azide group can be conjugated by either copper-catalyzed or copper-free click chemistry with alkynes and cycloalkynes.General properties
| Appearance: | dark crimson powder |
| Molecular weight: | 616.71 |
| CAS number: | 2628213-67-0 |
| Molecular formula: | C36H36N6O4 |
| Solubility: | good in polar organic solvents (DMF, DMSO, alcohols), low in water |
| Quality control: | NMR 1H, HPLC-MS (95%) |
| Storage conditions: | Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. |
| MSDS: | Download |
| Product specifications |
Spectral properties
| Excitation/absorption maximum, nm: | 570 |
| ε, L⋅mol−1⋅cm−1: | 93000 |
| Emission maximum, nm: | 591 |
| Fluorescence quantum yield: | 1.0 |
| CF260: | 0.62 |
| CF280: | 0.49 |
Product citations
- Ferguson, T.E.G.; Reihill, J.A.; Martin, S.L.; Walker, B. Novel Inhibitors and Activity-Based Probes Targeting Trypsin-Like Serine Proteases. Frontiers in Chemistry, 2022, 10, 782608. doi: 10.3389/fchem.2022.782608
- Feltes, M.; Moores, S.; Gale, S.E.; Krishnan, K.; Mydock-McGrane, L.; Covey, D.F.; Ory, D.S.; Schaffer, J.E. Synthesis and characterization of diazirine alkyne probes for the study of intracellular cholesterol trafficking. Journal of Lipid Research, 2019, 60(3), 707–716. doi: 10.1194/jlr.D091470
- Verardi, R.; Kim, J.-S.; Ghirlando, R.; Banerjee, A. Structural Basis for Substrate Recognition by the Ankyrin Repeat Domain of Human DHHC17 Palmitoyltransferase. Structure, 2017, 25(9), 1337–1347. doi: 10.1016/j.str.2017.06.018
- Bak, D.W.; Pizzagalli, M.D.; Weerapana, E. Identifying Functional Cysteine Residues in the Mitochondria. ACS Chemical Biology, 2017, 12(4), 947–957. doi: 10.1021/acschembio.6b01074
This Product is offered and sold for research purposes only. It has not been tested for safety and efficacy in food, drug, medical device, cosmetic, commercial or any other use. Supply does not express or imply authorization to use for any other purpose, including, without limitation, in vitro diagnostic purposes, in the manufacture of food or pharmaceutical products, in medical devices or in cosmetic products.
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