ROX azide, 5-isomer
Cat. # | Quantity | Price | Lead time | Buy this product |
---|---|---|---|---|
A1230 | 1 mg | $110 | in stock | |
B1230 | 5 mg | $165 | in stock | |
C1230 | 10 mg | $210 | in stock | |
D1230 | 25 mg | $285 | in stock | |
E1230 | 50 mg | $495 | in stock |
ROX azide is an alkyne-reactive derivative of ROX (Rhodamine X, Rhodamine 101) dye. ROX is a red-emitting fluorophore possessing high brightness and fluorescence quantum yield. This reagent is a pure 5-isomer. It is used for labeling alkyne and cycloalkyne-containing biomolecules via copper-catalyzed and copper-free click chemistry reactions.
This reagent is presented as a solid form and as a 10 mM solution in DMSO.
Absorption and emission spectra of ROX dye
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TAMRA azide, 6-isomer
Pure 6-isomer of tetramethylrhodamine (TAMRA) dye, azide derivative for copper-catalyzed and copper-free click chemistry reactions with alkynes.sulfo-Cyanine7 maleimide
Water-soluble near-infrared dye maleimide for the labeling of proteins and peptides.General properties
Appearance: | dark crimson powder / red solution |
Molecular weight: | 616.71 |
CAS number: | 2628213-67-0 |
Molecular formula: | C36H36N6O4 |
Solubility: | good in polar organic solvents (DMF, DMSO, alcohols), low in water |
Quality control: | NMR 1H, HPLC-MS (95%) |
Storage conditions: | Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. |
MSDS: | Download |
Product specifications |
Spectral properties
Excitation/absorption maximum, nm: | 570 |
ε, L⋅mol−1⋅cm−1: | 93000 |
Emission maximum, nm: | 591 |
Fluorescence quantum yield: | 1.0 |
CF260: | 0.62 |
CF280: | 0.49 |
Product citations
- Ferguson, T.E.G.; Reihill, J.A.; Martin, S.L.; Walker, B. Novel Inhibitors and Activity-Based Probes Targeting Trypsin-Like Serine Proteases. Frontiers in Chemistry, 2022, 10, 782608. doi: 10.3389/fchem.2022.782608
- Feltes, M.; Moores, S.; Gale, S.E.; Krishnan, K.; Mydock-McGrane, L.; Covey, D.F.; Ory, D.S.; Schaffer, J.E. Synthesis and characterization of diazirine alkyne probes for the study of intracellular cholesterol trafficking. Journal of Lipid Research, 2019, 60(3), 707–716. doi: 10.1194/jlr.D091470
- Verardi, R.; Kim, J.-S.; Ghirlando, R.; Banerjee, A. Structural Basis for Substrate Recognition by the Ankyrin Repeat Domain of Human DHHC17 Palmitoyltransferase. Structure, 2017, 25(9), 1337–1347. doi: 10.1016/j.str.2017.06.018
- Bak, D.W.; Pizzagalli, M.D.; Weerapana, E. Identifying Functional Cysteine Residues in the Mitochondria. ACS Chemical Biology, 2017, 12(4), 947–957. doi: 10.1021/acschembio.6b01074
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