DusQ 21 CPG 500
Cat. # | Quantity | Price | Lead time | Buy this product |
---|---|---|---|---|
3151-100mg | 100 mg | – | in stock | |
3151-1g | 1 g | $990 | in stock |
DusQ 21 is a quencher for the dyes in far red region of the spectrum. The dye is a xanthene derivative, unlike DusQ 1 or DusQ 2, that are azo dyes. It has a high extinction coefficient, and provides an outstanding quenching efficiency.
The controlled pore glass solid support allows to synthesize oligonucleotides carrying the dye moiety on 3’-terminus.
We recommend the use of ultramild, phenoxyacetyl protected monomers. As an alternative, post-synthetic labeling using NHS ester of DusQ 21 quencher can be used.
Usage
Coupling: Standard conditions identical to normal nucleobases.
Deprotection: 2 hours at room temperature using concentrated ammonia or potassium carbonate K2CO3 (50 mM solution in methanol).
Absorption spectrum of DusQ 21
Customers also purchased with this product
VIC phosphoramidite, 6-isomer
VIC is an asymmetrical xanthene dye with spectral properties similar to HEX and JOE. Useful as a label for qPCR probes.get free express delivery
Alkyne dT phosphoramidite
Phosphoramidite modifier for synthesizing oligonucleotides containing alkyne modification in the middle of the chain.get free express delivery
Alkyne CPG modifier 500
Solid support for the synthesis of 3'-modified oligonucleotides with alkyne group for Click Chemistry.General properties
Appearance: | dark blue beads |
Quality control: | 1H NMR of bound reagent, coupling testing with HPLC-MS |
Storage conditions: | 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Desiccate. Avoid prolonged exposure to light. |
MSDS: | Download |
Product specifications |
Spectral properties
Excitation/absorption maximum, nm: | 656 |
ε, L⋅mol−1⋅cm−1: | 72800 |
Oligo synthesis details
Pore size, Å: | 500 |
Typical loading, umol/g: | 50−80 |