BDP® 581/591 C11, lipid peroxidation probe
| Cat. # | Quantity | Price | Lead time | Buy this product |
|---|---|---|---|---|
| 5563-1mg | 1 mg |
$144.00
|
12 days |
BDP® 581/591 C11 is a lipophilic ratiometric probe based on boron dipyrromethene, designed for monitoring oxidative stress in living cells. Thanks to its fatty acid tail (C11), the probe efficiently incorporates into cellular membranes, where it selectively reacts with lipid hydroperoxides and reactive oxygen species.
Oxidation of the dye’s polyene chain shifts its fluorescence maximum from the red region of the spectrum (~594 nm) to the green region (~510 nm), enabling quantitative ratiometric analysis independent of probe concentration, excitation light intensity, and staining efficiency.
BDP® 581/591 C11 is suitable for long-term cell imaging and kinetic studies; it can be used to investigate ferroptosis and cell death, analyze oxidative stress induced by UV radiation, toxins, hypoxia, and other factors, screen for antioxidant compounds, and assess membrane integrity in metabolic studies.
Absorption and emission spectra of BDP® 581/591
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General properties
| Appearance: | purple solid |
| Molecular weight: | 504.43 |
| CAS number: | 217075-36-0 |
| Molecular formula: | C30H35BF2N2O2 |
| IUPAC name: | 11-[2,2-difluoro-12-[(1E,3E)-4-phenylbuta-1,3-dienyl]-3-aza-1-azonia-2-boranuidatricyclo[7.3.0.03,7]dodeca-1(12),4,6,8,10-pentaen-4-yl]undecanoic acid |
| Solubility: | DCM, DMSO, DMF, ethyl acetate |
| Quality control: | NMR 1H and HPLC-MS (95+%) |
| Storage conditions: | 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Desiccate. |
| MSDS: | Download |
| Product specifications |
Spectral properties
| Excitation/absorption maximum, nm: | 585 (reduced form) |
| Emission maximum, nm: | 594 (reduced form) |
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