SiRhius® 650 carboxylic acid

Cat. # Quantity Price Lead time
11S90 1 mg
$236.00
in stock
31S90 10 mg
$1240.00
in stock
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SiRhius® 650 is a silicon rhodamine (SiR) family fluorophore that exhibits far-red fluorescence. The dye is characterized by a high extinction coefficient, resistance to fading, and minimal photo- and cytotoxicity, making it indispensable for super-resolution microscopy (STED, SIM, PALM/STORM) and long-term live-cell imaging. Unlike many cyanine dyes, SiRhius 650 is stable under alkaline conditions.

SiRhius 650 carboxylic acid can be used as a reference standard and, after activation, for the synthesis of SiRhius 650-containing biomolecules (proteins, peptides, amino-modified oligonucleotides, etc.).

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General properties

Appearance: blue crystals
Molecular weight: 472.61
CAS number: 1426090-03-0
Molecular formula: C27H30N2O4Si
IUPAC name: 3,7-bis(dimethylamino)-5,5-dimethyl-3'-oxo-3'H,5H-spiro[dibenzo[b, e]siline-10,1'-isobenzofuran]-6'-carboxylic acid
Solubility: dichloromethane, ethyl acetate, methanol, acetonitrile, DMF
Quality control: NMR 1H and HPLC-MS (95+%)
Storage conditions: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Desiccate.
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 646
ε, L⋅mol−1⋅cm−1: 112000
Emission maximum, nm: 669
Fluorescence quantum yield: 0.57
CF260: 0.07
CF280: 0.02
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