Pico488 dsDNA Quantification Reagent, 200x

Cat. # Quantity Price Lead time
12010 100 uL –   in stock
42010 1 mL $360.00 in stock
62010 25 mL please inquire in stock

Pico488 is a DNA binding benzothiazole dye whose structure is identical to PicoGreen®. This reagent is a 200× solution in DMSO. The dye is a fluorescent sensor that is specific for double stranded DNA (dsDNA). Its absorption and emission in the fluorescein channel can be easily detected using cuvette fluorometers, well plate readers, and by dedicated DNA measurement fluorometers.

The dye exhibits a linear response of fluorescence to dsDNA concentrations in the range of low pg/mL to high ng/mL. The ready kit including quantification dye is also available.

Pico488 (Pico Green) excitation and emission spectra

Pico488 (Pico Green) excitation and emission spectra

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General properties

Appearance: orange solution
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 503
Emission maximum, nm: 526

Product citations

  1. Hiroki, H.; Ishii, Y.; Piao, J.; Namikawa, Y.; Masutani, M.; Honda, H.; Akahane, K.; Inukai, T.; Morio, T.; Takagi, M. Targeting Poly(ADP)Ribose Polymerase in BCR/ABL1-Positive Cells. Scientific Reports, 2023, 13(1), 7588. doi: 10.1038/s41598-023-33852-2
  2. Psotta, C.; Chaturvedi, V.; Gonzalez-Martinez, J.F.; Sotres, J.; Falk, M. Portable Prussian Blue-Based Sensor for Bacterial Detection in Urine. Sensors, 2023, 23(1), 388. doi: 10.3390/s23010388
  3. Cierzniak, A.; Kaliszewski, K.; Małodobra-Mazur, M. The Preliminary Evaluation of Epigenetic Modifications Regulating the Expression of IL10 in Insulin-Resistant Adipocytes. Genes, 2022, 13(2), 294. doi: 10.3390/genes13020294
  4. Cheng, A. G.; Ho, P.-Y.; Aranda-Díaz, A.; Jain, S.; Yu, F. B.; Meng, X.; Wang, M.; Iakiviak, M.; Nagashima, K.; Zhao, A.; Murugkar, P.; Patil, A.; Atabakhsh, K.; Weakley, A.; Yan, J.; Brumbaugh, A. R.; Higginbottom, S.; Dimas, A.; Shiver, A. L.; Deutschbauer, A.; Neff, N.; Sonnenburg, J. L.; Huang, K. C.; Fischbach, M. A. Design, Construction, and in Vivo Augmentation of a Complex Gut Microbiome. Cell, 2022, 185(19), 3617-3636.e19. doi: 10.1016/j.cell.2022.08.003
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