Pico488 dsDNA Quantification Kit

PCR and qPCR Nucleic acid quantification
Cat. # Quantity Price Lead time
1102-20
20 assays
–   in stock
1102-200
200 assays
$390.00 in stock
B1102
200 assays
$480.00 in stock
Sample request

Kit for quantitative measurement of double-stranded DNA in samples in the presence of RNA, proteins, and common contaminants. Pico488 allows to quantitate as little as low pg/mL of dsDNA. The range of linearity for DNA concentration measurements
is 1 pg/μL – 5 ng/μL so the sensitivity of this kit can be rated as Ultra High (UHS).

The kit contains Pico488 dye, buffer, and DNA standard for the measurements. It is compatible with fluorometers, fluorescent plate readers, cuvette and microvolume fluorometers.

Pico488 dsDNA quantification kit, 1102-200
Pico488 dsDNA quantification kit, 1102-200
Fluorescence of the Pico488 Quantitation Reagent upon binding with dsDNA, ssDNA and RNA
Pico488 fluorescence emission vs DNA concentration
Excitation and emission spectra of Pico488 complex with DNA

Ready kit manual

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General properties

Storage conditions: Store at temperature below 4°С. Do not freeze!
TN VED Code:
MSDS: Download

Kit

Storage time in month: 12

References

  1. Guan, J.; Lu, C.; Jin, Q.; Lu, H.; Chen, X.; Tian, L.; Zhang, Y.; Ortega, J.; Zhang, J.; Siteni, S.; Chen, M.; Gu, L.; Shay, J.W.; Davis, A.J.; Chen, Z.J.; Fu, Y.-X.; Li, G.-M. MLH1 Deficiency-Triggered DNA Hyperexcision by Exonuclease 1 Activates the cGAS-STING Pathway. Cancer Cell, 2021, 39(1), 109–121.e5. doi: 10.1016/j.ccell.2020.11.004
  2. Lu, C.; Guan, J.; Lu, S.; Jin, Q.; Rousseau, B.; Lu, T.; Stephens, D.; Zhang, H.; Zhu, J.; Yang, M.; Ren, Z.; Liang, Y.; Liu, Z.; Han, C.; Liu, L.; Cao, X.; Zhang, A.; Qiao, J.; Batten, K.; Chen, M.; Castrillon, D.H.; Wang, T.; Li, B.; Diaz, L.A.; Li, G.-M.; Fu, Y.-X. DNA Sensing in Mismatch Repair-Deficient Tumor Cells Is Essential for Anti-tumor Immunity. Cancer Cell, 2021, 39(1), 96–108.e6. doi: 10.1016/j.ccell.2020.11.006
  3. Caza, F.; Granger Joly de Boissel, P.; Villemur, R.; Betoulle, S.; St-Pierre, Y. Liquid biopsies for omics-based analysis in sentinel mussels. PLoS One, 2019, 14(10), e0223525. doi: 10.1371/journal.pone.0223525
  4. Crupi, A.N.; Nunnelee, J.S.; Taylor, D.J.; Thomas, A.; Vit, J.-P.; Riera, C.E.; Gottlieb, R.A.; Goodridge, H.S. Oxidative muscles have better mitochondrial homeostasis than glycolytic muscles throughout life and maintain mitochondrial function during aging. Aging, 2018, 10(11), 3327–3352. doi: 10.18632/aging.101643
Продукт предлагается и продаётся только в исследовательских целях. Продукт не проверяется на безопасность и эффективность в пищевых продуктах, лекарствах, медицинских приборах, косметических средствах, нет явного или подразумеваемого разрешения на использование для любых других целей, включая, помимо прочего, диагностические цели in vitro, для людей или животных или в коммерческих целях.
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