Sulfo-Cyanine3 maleimide
| Cat. # | Quantity | Price | Lead time | Buy this product |
|---|---|---|---|---|
| 11380 | 1 mg | $110.00 | in stock | |
| 21380 | 5 mg | $290.00 | in stock | |
| 41380 | 25 mg |
$690.00
|
in stock | |
| 51380 | 50 mg |
$1270.00
|
in stock | |
| 61380 | 100 mg |
$1990.00
|
in stock |
Sulfo-Cyanine3 maleimide is a water soluble, thiol reactive dye for the labeling with hydrophilic sulfo-Cyanine3 fluorophore. This is an analog of Cy3® maleimide.
This product is recommended for the labeling of antibodies and other labile proteins in mild, purely aqueous conditions. The dye is water soluble and does not require use of organic co-solvent.
A non-sulfonated Cyanine3 maleimide is available.
Sulfo-Cyanine3 maleimide
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General properties
| Appearance: | red powder |
| Molecular weight: | 776.96 |
| CAS number: | 1656990-68-9 |
| Molecular formula: | C36H41KN4O9S2 |
| IUPAC name: | 3H-Indolium, 2-[3-[1-[6-[[2-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)ethyl]amino]-6-oxohexyl]-1,3-dihydro-3,3-dimethyl-5-sulfo-2H-indol-2-ylidene]-1-propen-1-yl]-1,3,3-trimethyl-5-sulfo-, inner salt, potassium salt |
| Solubility: | soluble in water (0.39 M = 30 g/L), DMF, DMSO |
| Quality control: | NMR 1H, HPLC-MS (95+%) |
| Storage conditions: | Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate. |
| MSDS: | Download |
| Product specifications |
Spectral properties
| Excitation/absorption maximum, nm: | 548 |
| ε, L⋅mol−1⋅cm−1: | 162000 |
| Emission maximum, nm: | 563 |
| Fluorescence quantum yield: | 0.1 |
| CF260: | 0.03 |
| CF280: | 0.06 |
Product citations
- Ast, J.; Novak, A.N.; Podewin, T.; Fine, N.H.F.; Jones, B.; Tomas, A.; Birke, R.; Roßmann, K.; Mathes, B:; Eichhorst, J.; Lehmann, M.; Linnemann, A.K.; Hodson, D.J.; Broichhagen, J. An expanded LUXendin color palette for GLP1R detection and visualization in vitro and in vivo. ChemRxiv, preprint. doi: 10.33774/chemrxiv-2021-7rngq
- Mohale, M.; Gundampati, R.K.; Thallapuranam, S.; Heyes, C.D. Site-specific labeling and functional efficiencies of human fibroblast growth Factor-1 with a range of fluorescent dyes in the flexible N-Terminal region and a rigid β-turn region. Analytical Biochemistry, 2022, 640, 114524. doi: 10.1016/j.ab.2021.114524
- Bauer, B.W.; Davidson, I.F.; Canena, D.; Wutz, G.; Tang, W.; Litos, G.; Horn, S.; Hinterdorfer, P.; Peters, J.-M. Cohesin mediates DNA loop extrusion by a “swing and clamp” mechanism. Cell, 2021, 184(21), 5448--5464.e22. doi: 10.1016/j.cell.2021.09.016
- Deckard, C.E.; Sczepanski, J.T. Reversible chromatin condensation by the DNA repair and demethylation factor thymine DNA glycosylase. Nucleic Acids Research, 2021, 49(5), 2450–2459. doi: 10.1093/nar/gkab040
Cy® is a trademark of GE Healthcare.
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