Cyanine3 alkyne
| Cat. # | Quantity | Price | Lead time | Buy this product |
|---|---|---|---|---|
| A10B0 | 1 mg | $125 | in stock | |
| B10B0 | 5 mg | $260 | in stock | |
| C10B0 | 10 mg | $325 | in stock | |
| D10B0 | 25 mg |
$510
|
in stock | |
| E10B0 | 50 mg |
$895
|
in stock | |
| F10B0 | 100 mg |
$1490
|
in stock |
Cyanine3 alkyne is a bright and photostable fluorophore for сlick сhemistry, an analog of Cy3®. This dye can be attached to nearly any molecule bearing azide group via copper-catalyzed click-reaction.
This alkyne is non-water-soluble. However, when used with organic co-solvent (DMSO or DMF), this dye can be efficiently attached to water-soluble molecules such as proteins or peptides.
Cyanine3 absorbance and emission spectra
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DusQ 2 NHS ester
DusQ 2 dark quencher with a quenching range from 560 - 670 nm with primary amine reactivity for synthesis of FRET probes. This NHS ester can be coupled to various molecules bearing amino groups.Cyanine3 carboxylic acid
The free carboxylic acid of Cyanine3 dye. Non-sulfonated dye, with good solubility in organic solvents, and limited aqueous solubility.Azidobutyric acid NHS ester
Activated NHS ester for azido-labeling of peptides and proteins.General properties
| Appearance: | red powder |
| Molecular weight: | 530.14 |
| Molecular formula: | C33H40ClN3O |
| Solubility: | soluble in organic solvents (DMF, DMSO, dichloromethane), , practically insoluble in water (50 mg/L = 80 uM) |
| Quality control: | NMR 1H (95%), HPLC-MS |
| Storage conditions: | Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate. |
| MSDS: | Download |
| Product specifications |
Spectral properties
| Excitation/absorption maximum, nm: | 555 |
| ε, L⋅mol−1⋅cm−1: | 150000 |
| Emission maximum, nm: | 570 |
| Fluorescence quantum yield: | 0.31 |
| CF260: | 0.04 |
| CF280: | 0.09 |
Product citations
- Guarin, M.; Faelens, R.; Giusti, A.; De Croze, N.; Léonard, M.; Cabooter, D.; Annaert, P.; de Witte, P.; Ny, A. Spatiotemporal Imaging and Pharmacokinetic of Fluorescent Compounds in Zebrafish Eleuthero-Embryos After Different Routes of Administration. Scientific Reports, 2021, 11(1), 12229. doi: 10.1038/s41598-021-91612-6.
- Guarin, M.; Ny, A.; De Croze, N.; Maes, J.; Léonard, M.; Annaert, P.; de Witte, P. A. M. Pharmacokinetics in Zebrafish Embryos (ZFE) Following Immersion and Intrayolk Administration: A Fluorescence-Based Analysis. Pharmaceuticals, 2021, 14(6), 576. doi: 10.3390/ph14060576
- Guarin, M.; Faelens, R.; Giusti, A.; De Croze, N.; Léonard, M.; Cabooter, D.; Annaert, P.; de Witte, P.; Ny, A. Spatiotemporal imaging and pharmacokinetics of fluorescent compounds in zebrafish eleuthero-embryos after different routes of administration. Scientific Reports, 2021, 11, 12229. doi: 10.1038/s41598-021-91612-6
- Navarro, L.A.; French, D.L.; Zauscher, S. Synthesis of Modular Brush Polymer-Protein Hybrids using Diazotransfer and Copper Click Chemistry. Bioconjugate Chemistry, 2018, 29(8), 2594–2605. doi: 10.1021/acs.bioconjchem.8b00309
Cy2® is a trademark of GE Healthcare.
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