AF 343 (Coumarin) X carboxylic acid

Cat. # Quantity Price Lead time
12690 1 mg $105 in stock
22690 5 mg $165 in stock
42690 25 mg $285 in stock
52690 50 mg $495 in stock
62690 100 mg $880 in stock
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AF 343 (Coumarin) is a blue-emitting fluorophore used as a laser dye. The fluorophore can serve as a FRET donor for FAM (fluorescein).

Absorption and emission spectra of AF 343 (Coumarin)

Absorption and emission spectra of AF 343 (Coumarin)

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AF 343 (Coumarin) X azide

AF 343 (Coumarin) is a blue emitting fluorophore that can serve as a FRET donor for fluorescein (FAM). This azide derivative can be conjugated with alkynes by сlick chemistry. An extended linker arm between the fluorophore and the azide group enhances solubility and provides spatial separation between the dye and the biomolecule.

General properties

Appearance: yellow crystals
Molecular weight: 398.45
CAS number: 946123-11-1
Molecular formula: C22H26N2O5
IUPAC name: 6-({4-Oxo-3-oxa-13-azatetracyclo[7.7.1.02,7.013,17]heptadeca-1,5,7,9(17)-tetraen-5-yl}carbonylamino)hexanoic acid
Solubility: Well soluble in DMF, DMSO, moderately soluble in DCM, DCE, EtOAc, insoluble in diethyl ether.
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 437
ε, L⋅mol−1⋅cm−1: 39000
Emission maximum, nm: 477
Fluorescence quantum yield: 0.63
CF260: 0.29
CF280: 0.24
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