BDP FL alkyne
| Cat. # | Quantity | Price | Lead time | Buy this product |
|---|---|---|---|---|
| A14B0 | 1 mg | $110.00 | in stock | |
| B14B0 | 5 mg | $210.00 | in stock | |
| C14B0 | 10 mg | $310.00 | in stock | |
| D14B0 | 25 mg |
$410.00
|
in stock | |
| E14B0 | 50 mg |
$695.00
|
in stock | |
| F14B0 | 100 mg |
$1190.00
|
in stock |
Alkyne derivative of BDP FL, an analog of BODIPY® FL alkyne. BDP FL is a borondipyrromethene dye, a bright and photostable fluorophore which emits in fluorescein (FAM) channel. Unlike FAM, BDP FL is very photostable. Its brightness is similar to fluorescein.
This alkyne can be conjugated with a number of azide-containing molecules by copper-catalyzed Click Chemistry.
BDP FL absorption and emission spectra
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ROX alkyne, 5-isomer
Rhodamine X (ROX, Rhodamine 101) alkyne derivative for copper catalyzed Click chemistry. ROX is a bright red-emitting dye.Biotin alkyne
Biotin alkyne is a reactive affinity label which can be attached to biomolecules via Click Chemistry.BDP FL DBCO
BDP FL DBCO is a dye cyclooctyne for copper free Click chemistry reaction with azides. Absorption and emission wavelengths of BDP FL correspond to those of fluorescein (FAM), but BDP FL is significantly more photostable.General properties
| Appearance: | orange solid |
| Mass spec M+ increment: | 329.1 |
| Molecular weight: | 329.15 |
| CAS number: | 302795-84-2, 2006345-30-6 |
| Molecular formula: | C17H18BF2N3O |
| IUPAC name: | |
| Solubility: | Good in organic solvents (DMF, DMSO, dichlromethane), limited in water |
| Quality control: | NMR 1H, HPLC-MS (95%) |
| Storage conditions: | Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate. |
| MSDS: | Download |
| Product specifications |
Spectral properties
| Excitation/absorption maximum, nm: | 503 |
| ε, L⋅mol−1⋅cm−1: | 92000 |
| Emission maximum, nm: | 509 |
| Fluorescence quantum yield: | 0.97 |
| CF260: | 0.015 |
| CF280: | 0.027 |
Product citations
- Abukar, T.; Rahmani, S.; Thompson, N.K.; Antonescu, C.N.; Wakarchuk, W.W. Development of BODIPY labelled sialic acids as sialyltransferase substrates for direct detection of terminal galactose on N- and O-linked glycans. Carbohydrate Research, 2021, 500, 108249. doi: 10.1016/j.carres.2021.108249
- Merlo, R.; Caprioglio, D.; Cillo, M.; Valenti, A.; Mattossovich, R.; Morrone, C.; Massarotti, A.; Rossi, F.; Miggiano, R.; Leonardi, A.; Minassi, A.; Perugino, G. The SNAP-tag technology revised: an effective chemo-enzymatic approach by using a universal azide-based substrate. Journal of Enzyme Inhibition and Medicinal Chemistry, 2021, 36(1), 85–97. doi: 10.1080/14756366.2020.1841182
- Du, T.; Buenbrazo, N.; Kell, L.; Rahmani, S.; Sim, L.; Withers, S.G.; DeFrees, S.; Wakarchuk, W.;. A Bacterial Expression Platform for Production of Therapeutic Proteins Containing Human-like O-Linked Glycans. Cell Chemical Biology, 2019, 26(2), 203–212.e5. doi: 10.1016/j.chembiol.2018.10.017
- Daryaee, F.; Zhang, Z.; Gogarty, K.R.; Li, Y.; Merino, J.; Fisher, S.L.; Tonge, P.J. A quantitative mechanistic PK/PD model directly connects Btk target engagement and in vivo efficacy. Chemical Science, 2017, 8(5), 3434–3443. doi: 10.1039/c6sc03306g
BODIPY® is a trademark of Life Technologies
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