BDP FL alkyne
| Cat. # | Quantity | Price | Lead time | Buy this product |
|---|---|---|---|---|
| A14B0 | 1 mg | $110.00 | in stock | |
| B14B0 | 5 mg | $210.00 | in stock | |
| C14B0 | 10 mg | $310.00 | in stock | |
| D14B0 | 25 mg |
$410.00
|
in stock | |
| E14B0 | 50 mg |
$695.00
|
in stock | |
| F14B0 | 100 mg |
$1190.00
|
in stock |
Alkyne derivative of BDP FL, an analog of BODIPY® FL alkyne. BDP FL is a borondipyrromethene dye, a bright and photostable fluorophore which emits in fluorescein (FAM) channel. Unlike FAM, BDP FL is very photostable. Its brightness is similar to fluorescein.
This alkyne can be conjugated with a number of azide-containing molecules by copper-catalyzed Click Chemistry.
BDP FL absorption and emission spectra
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AmdU (5-azidomethyl-2'-deoxyuridine)
Azidomethyldeoxyuridine (AmdU) is an azide containing nucleoside that is incorporated into nascent DNA by cellular polymerases. The azide groups attached to DNA this way can be subsequently modified with alkynes or cycloalkynes via copper-catalyzed or strain promoted Click chemistry.dsGreen Gel Staining Solution, 10000×
dsGreen, a SYBR Green I analog for staining dsDNA in gelsFAM NHS ester, 6-isomer
Activated N-hydroxysuccinimide ester of fluorescein (FAM), pure 6-isomer.General properties
| Appearance: | orange solid |
| Mass spec M+ increment: | 329.1 |
| Molecular weight: | 329.15 |
| CAS number: | 302795-84-2, 2006345-30-6 |
| Molecular formula: | C17H18BF2N3O |
| IUPAC name: | |
| Solubility: | Good in organic solvents (DMF, DMSO, dichlromethane), limited in water |
| Quality control: | NMR 1H, HPLC-MS (95%) |
| Storage conditions: | Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate. |
| MSDS: | Download |
| Product specifications |
Spectral properties
| Excitation maximum, nm: | 503 |
| ε, L⋅mol−1⋅cm−1: | 92000 |
| Emission maximum, nm: | 509 |
| Fluorescence quantum yield: | 0.97 |
| CF260: | 0.015 |
| CF280: | 0.027 |
Product citations
- Du, T.; Buenbrazo, N.; Kell, L.; Rahmani, S.; Sim, L.; Withers, S.G.; DeFrees, S.; Wakarchuk, W.;. A Bacterial Expression Platform for Production of Therapeutic Proteins Containing Human-like O-Linked Glycans. Cell Chemical Biology, 2019, 26(2), 203–212.e5. doi: 10.1016/j.chembiol.2018.10.017
- Daryaee, F.; Zhang, Z.; Gogarty, K.R.; Li, Y.; Merino, J.; Fisher, S.L.; Tonge, P.J. A quantitative mechanistic PK/PD model directly connects Btk target engagement and in vivo efficacy. Chemical Science, 2017, 8(5), 3434–3443. doi: 10.1039/c6sc03306g
- Kubota, T.; Durek, T.; Dang, B.; Finol-Urdaneta, R.K.; Craik, D.J.; Kent, S.B.H.; French, R.J.; Bezanilla, F.; Correa, A.M. Mapping of voltage sensor positions in resting and inactivated mammalian sodium channels by LRET. Proceedings of the National Academy of Sciences of the U.S.A., 2017, 114(10), E1857–1865. doi: 10.1073/pnas.1700453114
BODIPY® is a trademark of Life Technologies
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