BDP® 650/665-X-NHS ester

Cat. # Quantity Price Lead time
1E420 1 mg $125 in stock
2E420 5 mg $260 in stock
4E420 25 mg $510 in stock
5E420 50 mg $895 in stock
6E420 100 mg $1490 in stock
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BDP® 650/665 is a borondipyrromethene dye with far-red excitation and emission. The dye has a good molar extinction coefficient and emission quantum yield.

The NHS ester can be conjugated with amine groups of proteins, peptides, and other molecules. The molecule contains an additional aminohexanoic acid linker.

Absorption and emission spectra of BDP 650/665

Absorption and emission spectra of BDP 650/665

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DBCO-NHS ester

Azodibenzocyclooctyne (DBCO, ADIBO) reagent for strain-promoted copper-free click chemistry (SPAAC). The reagent contains an NHS ester function for the attachment of the cyclooctyne to various molecules.

THPTA ligand

THPTA is a water-soluble ligand for Cu(I)-catalyzed click chemistry. The ligand stabilizes copper in its Cu(I) oxidation state. Due to high aqueous solubility, reactions with this ligand do not require an organic co-solvent.

BDP® 650/665 alkyne

BDP 650/665 is a bright borondipyrromethene red-emitting dye. The terminal ethynyl group of BDP 650/665 alkyne can be easily conjugated with various azides using a copper-catalyzed click reaction.

General properties

Appearance: dark colored solid
Mass spec M+ increment: 528.2
Molecular weight: 643.45
CAS number: 235439-04-0; 1616842-78-4
Molecular formula: C33H32N5BF2O6
Solubility: good in DMF, DMSO, low in water
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 12 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 649
ε, L⋅mol−1⋅cm−1: 94000
Emission maximum, nm: 667
Fluorescence quantum yield: 0.52
CF260: 0.04
CF280: 0.04

Product citations

  1. Roussel, S.; Grenier, P.; Chénard, V.; Bertrand, N. Dual-Labelled Nanoparticles Inform on the Stability of Fluorescent Labels In Vivo. Pharmaceutics 2023, 15 (3), 769., 2023, 15(3), 769. doi: 10.3390/pharmaceutics15030769
  2. Daumar, P.; Goisnard, A.; Dubois, C.; Roux, M.; Depresle, M.; Penault-Llorca, F.; Bamdad, M.; Mounetou, E. Chemical biology fluorescent tools for in vitro investigation of the multidrug resistant P-glycoprotein (P-gp) expression in tumor cells. RSC Advances, 2023, 13(39), 27016-27035. doi: 10.1039/d3ra05093a
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