BDP FL tetrazine

Cat. # Quantity Price Lead time
114E0 1 mg $110.00 in stock
214E0 5 mg $290.00 in stock
414E0 25 mg $690.00 in stock
514E0 50 mg $1270.00 in stock
614E0 100 mg $1990.00 in stock

Inverse electron demand Diels-Alder reaction (ied-DA) with tetrazines is a promising tool for the conjugation of biomolecules. The reaction takes place between tetrazine as an electron acceptor heterodiene, and a strained dienophile, such as trans-cyclooctene, cyclopropene, or some cyclooctynes.

Methyltetrazine provides greater stability in buffers than unsubstituted tetrazine. The rate of its reaction with cycloalkenes still beats almost all other conjugation reaction rates by a factor of magnitudes.

BDP FL is a bright dye for fluorescein (FAM) channel. Using BDP FL tetrazine, the dye can be conjugated with molecules bearing strained olefins.

Absorption and emission spectra of BODIPY FL

Absorption and emission spectra of BODIPY FL

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Cyanine7 tetrazine

Near infrared Cyanine7 dye derivative containing tetrazine group for TCO ligation.

General properties

Appearance: red crystalline solid
Mass spec M+ increment: 447.2
Molecular weight: 475.3
Molecular formula: C24H24N7BF2O
Solubility: good in DCM, DMSO, DMF
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.
MSDS: Download
Product specifications

Spectral properties

Excitation maximum, nm: 503
ε, L⋅mol−1⋅cm−1: 92000
Emission maximum, nm: 509
Fluorescence quantum yield: 0.97
CF260: 0.015
CF280: 0.027
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