Cell biology reagents

Cell biology reagents / product groups & items in this category
Dyes and reagents for cell biology: cell markers and indicators, substances for metabolic labeling, inhibitors, etc.

Nuclear stains

Cell-membrane permeable and impermeant DNA dyes for specific staining nuclei in live or fixed cells.

Plasma membrane stains

Lipophilic dyes for plasma membrane staining and visualization of cell boundaries and morphology.
  • DND-167, blue fluorescent pH indicator
    Blue fluorescent pH-sensitive dye for staining acidic organelles (lysosomes and late endosomes) in living cells.
  • LumiTracker® Lyso Green
    Green-fluorescent dye for visualization of lysosomes in living cells and other cell organelles with a low pH. Analog of LysoTracker™ Green DND-26.
  • LumiTracker® Lyso Red
    Red-fluorescent reagent for labeling and tracking lysosomes and other acidic organelles with low internal pH in live cells. Analog of LysoTracker™ Red DND-99.
  • (E,E)-3,5-Bis(phenylethenyl)-BDP lipid stain
    A non-functionalized 3,5-substituted borondipyrromethene derivative with a Stokes shift of 13 nm and an emission spectrum in the red spectrum range.
  • BDP® 493/503 lipid stain
    BDP 493/503 is a lipophilic green fluorescent dye for the staining and tracing of cell membranes, lipids, and oils.
  • BDP® 505/515 lipid stain
    BDP 505/515 is a lipid staining dye for cell membranes. It has a high fluorescence quantum yield, and is very photostable.
  • BDP® 630/650 lipid stain
    Far-red fluorescent dye BDP 630/650 for staining of lipids and and other lipophilic compounds.
  • BDP® 650/665 lipid stain
    Hydrophobic borondipyrromethene dye BDP 650/665 for staining of lipids and lipophilic compounds.
  • BDP® FL ceramide
    Fluorescent derivative of sphingosine with emission in the green spectrum region for visualization of the Golgi apparatus in cells.
  • BDP® TMR ceramide
    Fluorescent derivative of sphingosine with emission in the orange spectrum region for visualization of the Golgi apparatus in cells.
  • BDP® TR ceramide
    Fluorescent derivative of sphingosine with emission in the red spectrum region for visualization of the Golgi apparatus in cells.
  • BDP® TR methyl ester
    BDP TR methyl ester is a lipophilic counterstain for GFP. Сell-permeable dye that stains mitochondria and endomembranous organelles, but not plasma membrane.
  • Deep-Red Fluorescent Nissl Stain
    Far-red fluorescent Nissl stain for visualization and assessment of neural tissue morphology.
  • LumiTracker® ER Green
    Green fluorescent stain for selective labeling of endoplasmic reticulum (ER) in live cells.
  • LumiTracker® ER Red
    Red fluorescent stain for selective labeling of endoplasmic reticulum (ER) in live cells.
  • LumiTracker® Mito Green FM
    Сell-permeant, cationic, green-fluorescent dye for staining active mitochondria in living cells in a potential-dependent manner.
  • LumiTracker® Mito JC-1
    The cationic carbocyanine dye that is widely used as an indicator of mitochondrial membrane potential to study apoptosis and monitor the health of mitochondria.
  • LumiTracker® Mito Orange CMTMRos
    Сell-permeant, cationic, orange-fluorescent dye for staining active mitochondria in living cells in a potential-dependent manner. The stain is compatible with aldehyde fixation.
  • LumiTracker® Mito Red CMXRos
    Сell-permeant, cationic, red-fluorescent dye for staining active mitochondria in living cells in a potential-dependent manner. The stain is compatible with aldehyde fixation.
  • LumiTracker® Mito Red FM
    Сell-permeant, cationic, red-fluorescent dye for staining active mitochondria in living cells in a potential-dependent manner.
  • LumiTracker® Mito Rhodamine 123
    Rhodamine 123 is a cell-permeant, green-fluorescent dye that stains mitochondria in living cells in a membrane potential-dependent manner.
  • LumiTracker® Mito TMRE
    Tetramethylrhodamine ethyl ester (TMRE) is an orange-red fluorescent dye for staining active mitochondria and quantitate mitochondrial membrane potential in live cells.
  • SynaptoProbe Green
    SynaptoProbe Green is an analog of FM®1-43, a widely used green fluorescent dye for staining synaptic vesicles and studying synaptic activity in the synapses or neuromuscular junctions.
  • SynaptoProbe Red
    SynaptoProbe Red is an analog of FM®4-64, a widely used red fluorescent dye for staining synaptic vesicles and studying synaptic activity in the synapses or neuromuscular junctions.
  • TAMRA-2,4-dinitroaniline (TMR-DN)
    TAMRA-2,4-dinitroaniline is a probe for visualizing RNA in living cells.

Cell tracing and tracking

Our dyes for anterograde and retrograde tracing of living and fixed cells and cell tracking.
  • CFDA SE cell tracing kit
    The ready-to-use kit for fluorescent labeling and long-term tracing of cells. CFDA SE is commonly used for measuring and tracking cell divisions.
  • PKH Dyes Diluent
    Diluent for PKH series of membrane labeling dyes.
  • PKH2 cell membrane labeling kit
    The ready-to-use kit to label cell membranes with green fluorescent PKH2 dye for evaluating cell migration or proliferation.
  • PKH26 cell membrane labeling kit
    The ready-to-use kit to label cell membranes with red fluorescent PKH26 dye for evaluating cell migration or proliferation.
  • PKH800 cell membrane labeling kit
    The ready-to-use kit to label cell membranes with near-infrared fluorescent PKH800 dye for evaluating cell migration or proliferation.
  • (5,6)-FAM diacetate NHS ester
    Amine-reactive fluorescein (FAM) derivative, a mixture of 5- and 6-isomers. The reagent becomes brightly green fluorescent once it is hydrolyzed while diffusing into cells. A fluorescent tracer.
  • AF 594 biocytin
    AF 594 biocytin is a cell-impermeant fixable polar tracer with red emission that can be used to examine plasma membrane permeability, pinocytosis, transport through gap junctions, and cell-cell or cell-liposome fusion.
  • Biocytin hydrochloride
    Lysine derivative of biotin for conjugation with avidin or streptavidin, neuroanatomical tracer.
  • CM-DiI, lipophilic tracer
    Orange-red fluorescent lipophilic dye for membrane labeling and cell tracking. Unlike other membrane dyes, CM-DiI persists in cells after their fixation and permeabilization.
  • DiA, lipophilic tracer
    Wide spectrum fluorescent lipophilic dye for membrane labeling and cell tracing.
  • DiD, lipophilic tracer
    Far-red fluorescent lipophilic dye for membrane labeling and cell tracing.
  • DiI, lipophilic tracer
    Orange-red fluorescent lipophilic dye for membrane labeling and cell tracing.
  • DiO, lipophilic tracer
    Green fluorescent lipophilic dye for membrane labeling and cell tracing.
  • DiR, lipophilic tracer
    Near-infrared fluorescent lipophilic dye for membrane labeling and cell tracing.
  • Neuro-DiO, lipophilic tracer
    Non-aggregating green fluorescent lipophilic dye for membrane labeling and cell tracing.
  • RAPID DiI, lipophilic tracer
    Orange-red fluorescent lipophilic dye for cell tracing with fast migration into membranes, an analog of FAST DiI™.
  • RAPID DiO, lipophilic tracer
    Green fluorescent lipophilic dye for cell tracing with fast migration into membranes, an analog of FAST DiO™.

Cell viability indicators

Reagents and ready-to-use kits for studying cell viability and apoptosis by flow cytometry and microscopy.

ROS indicators

Cell permeant fluorogenic dyes for detection of reactive oxygen species (ROS) in live cells by flow cytometry, microscopy, or fluorimetry.

Ion and pH indicators

Small fluorogenic molecules for indicating specific ions inside cells in vivo. Cell permeant indicators for Ca-, Fe-ions, pH, and others.

Potentiometric probes

Voltage-sensitive dyes for measurement of spatial and temporal fluctuations in membrane potential across the membrane of large cell populations, single cells, and cell organelles.
  • Di-4-ANEPPS, potentiometric probe
    Fast-response potential-sensitive fluorescent probe for imaging functional activity of neurons and heart cells. The dye is quickly internalized by cells and is well-suited for short-term experiments.
  • Di-8-ANEPPS, potentiometric probe
    Fast-response potential-sensitive fluorescent probe for imaging functional activity of neurons and heart cells. The dye has more lipophilic properties than other dyes of the ANEP family, making it well-suited for long-term experiments.
  • RH 237, potentiometric probe
    Fast-response potential-sensitive fluorescent probe for imaging functional activity of mitochondria, neurons, and heart cells.

Cell type-specific markers

Small-molecule fluorescent markers for different types of cells. A fast and well-permeant to live cells and tissues alternative to antibody labeling.
  • Deep-Red Fluorescent Nissl Stain
    Far-red fluorescent Nissl stain for visualization and assessment of neural tissue morphology.
  • LumiCell CDr20 Microglia Stain
    CDr20 is a turn-on fluorescent chemical probe for specific labeling and visualizing microglia in cell cultures and live brains.
  • LumiCell Reticulocyte Stain
    LumiCell Reticulocyte Stain is a ready-to-use Thiazole Orange solution for determining a percentage of reticulocytes in human peripheral blood with microscopy and flow cytometry.

Immunofluorescence

Reagents for immunofluorescence applications: fluorescent labeled derivatives of tyramide for signal amplification (TSA), biotin, and streptavidin for Western Blotting, immunoassay, immunochemistry, and in situ hybridization.
  • AF 488 streptavidin
    AF 488 conjugate of streptavidin, a high-affinity biotin-binding protein, for immunofluorescence, western blots, microplate assays, and other applications use.
  • AF 488 tyramide
    A tyramide derivative of AF 488, a green fluorescent reagent widely used for tyramide signal amplification (TSA) in IHC, ICC, and FISH.
  • AF 594 streptavidin
    AF 594 conjugate of streptavidin, a high-affinity biotin-binding protein, for immunofluorescence, western blots, microplate assays, and other applications use.
  • AF 594 tyramide
    A tyramide derivative of AF 594, a red fluorescent reagent widely used for tyramide signal amplification (TSA) in IHC, ICC, and FISH.
  • AMCA streptavidin
    AMCA conjugate of streptavidin, a high-affinity biotin-binding protein, for immunofluorescence, western blots, microplate assays, and other applications use.
  • sulfo-Cyanine3 streptavidin
    sulfo-Cyanine3 conjugate of streptavidin, a high-affinity biotin-binding protein, for immunofluorescence, western blots, microplate assays, and other applications use.
  • sulfo-Cyanine3 tyramide
    A tyramide derivative of sulfo-Cyanine3, an orange fluorescent reagent widely used for tyramide signal amplification (TSA) in IHC, ICC, and FISH.
  • sulfo-Cyanine3-PEG3-biotin
    Conjugate of hydrophilic sulfo-Cyanine3 dye with biotin, affinity label for avidin/streptavidin.
  • sulfo-Cyanine5 streptavidin
    sulfo-Cyanine5 conjugate of streptavidin, a high-affinity biotin-binding protein, for immunofluorescence, western blots, microplate assays, and other applications use.
  • sulfo-Cyanine5 tyramide
    A tyramide derivative of sulfo-Cyanine5, a far-red fluorescent reagent widely used for tyramide signal amplification (TSA) in IHC, ICC, and FISH.
  • sulfo-Cyanine5-PEG3-biotin
    Biotin conjugate of the far-red fluorescent sulfo-Cyanine5 dye.
  • sulfo-Cyanine5.5 tyramide
    A tyramide derivative of sulfo-Cyanine5.5, a far-red fluorescent reagent widely used for tyramide signal amplification (TSA) in IHC, ICC, and FISH.
  • sulfo-Cyanine7 tyramide
    A tyramide derivative of sulfo-Cyanine7, a near-infrared fluorescent reagent widely used for tyramide signal amplification (TSA) in IHC, ICC, and FISH.
  • 4AZP (4-Azido-L-phenylalanine)
    Unnatural L-phenylalanine derivative with an azide moiety for nascent protein synthesis detection via copper-catalyzed and copper-free click chemistry.
  • 5-Ethynyl-uridine (EU)
    Uridine alkyne derivative for monitoring and investigation of RNA transcription in cells.
  • AHA (L-Azidohomoalanine)
    Noncanonical amino acid analog of methionine with an azide moiety for nascent protein synthesis detection via copper-catalyzed and copper-free click chemistry.
  • Ac4GalNAl (N-(4-pentynoyl)-galactosamine-tetraacylated)
    An alkyne-functionalized monosaccharide for metabolic labeling and studying the cellular trafficking of labeled proteins and proteomic analysis.
  • Ac4GalNAz (N-Azidoacetylgalactosamine-tetraacylated)
    An azide-functionalized monosaccharide for metabolic labeling and studying the cellular trafficking of labeled proteins and proteomic analysis.
  • Ac4GlcNAl (N-4-pentynoyl-glucosamine-tetraacylated)
    An alkyne-functionalized monosaccharide for metabolic labeling and studying the cellular trafficking of labeled proteins and proteomic analysis.
  • Ac4GlcNAz (N-Azidoacetylglucosamine-tetraacylated)
    An azide-functionalized monosaccharide for metabolic labeling and studying the cellular trafficking of labeled proteins and proteomic analysis.
  • Ac4ManNAl (N-(4-pentynoyl)-mannosamine-tetraacylated)
    An alkyne-functionalized monosaccharide for metabolic labeling and studying the cellular trafficking of labeled proteins and proteomic analysis.
  • Ac4ManNAz (N-Azidoacetylmannosamine-tetraacylated)
    An azide-functionalized monosaccharide for metabolic labeling and studying the cellular trafficking of labeled proteins and proteomic analysis.
  • AmdU (5-Azidomethyl-2'-deoxyuridine)
    Azidomethyldeoxyuridine (AmdU) is an azide-contained nucleoside that is incorporated into nascent DNA by cellular polymerases. The azide groups attached to DNA this way can be subsequently modified with alkynes or cycloalkynes via copper-catalyzed or strain-promoted click reaction.
  • BrdU (5-Bromo-2′-deoxyuridine)
    BrdU is a synthetic analog of thymidine for studying de novo DNA synthesis and cell proliferation.
  • EdU (5-Ethynyl-2'-deoxyuridine)
    EdU is a nucleoside that is incorporated into replicated DNA by cellular enzymes. After it, DNA contained in the cells can be developed by click chemistry reaction with fluorescent dye azides to reveal cell proliferation.
  • F-ara-EdU (2’-Deoxy-2’-fluoro-5-ethynyluridine)
    F-ara-EdU is a synthetic analog of thymidine used to study de novo DNA synthesis and cell proliferation. It is a less cytotoxic alternative for BrdU and EdU.
  • HPG (L-Homopropargylglycine)
    Noncanonical amino acid analog of methionine with a terminal alkyne moiety for nascent protein synthesis detection.
  • TE-L-Tyrosine (FET-precursor)
    O-Tosyloxyethyl-N-trityl-tyrosine tert-butyl ester (also known as TET) is a precursor for O-(2-[18F]fluoroethyl)-L-tyrosine (FET) - a widely used F18-labeled amino acid tracer for positron emission tomography and computed tomography (PET/CT).
  • VU (5-Vinyl-uridine)
    Uridine derivative with a terminal alkene group for monitoring and investigating cell RNA transcription.
  • VdU (5-Vinyl-2'-deoxyuridine)
    VdU is a synthetic analog of thymidine for studying de novo DNA synthesis and cell proliferation.

Mounting media for microscopy

Fluorescence mounting media for microscopy applications.
Group tags Microscopy
  • (E/Z)-4-Hydroxytamoxifen
    (E/Z)-4-Hydroxytamoxifen (4-OHT, afimoxifene) is a selective estrogen receptor (ER) modulator, an active tamoxifen metabolite widely used for inducible genome manipulation.
  • Annexin V, His Tag
    Recombinant Human Annexin V for producing fluorescent Annexin V conjugates and inhibition of the procoagulant and proinflammatory activities of the apoptotic cells.
  • BAPTA AM, calcium chelator
    Cell-permeable acetoxymethyl ester (AM) form of BAPTA, a highly selective calcium chelator for cell signaling studies.
  • DREADD agonist 21 dihydrochloride
    An agonist for selective activation of hM3Dq (excitatory) and hM4Di (inhibitory) DREADDs. A widely used chemogenetic tool for remotely controlling neuronal activity.
  • Vacuolin-1
    Cell-permeable inhibitor of calcium-dependent lysosomal exocytosis.
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