Cyanine5.5 NHS ester
| Cat. # | Quantity | Price | Lead time | Buy this product |
|---|---|---|---|---|
| 17020 | 1 mg | $125 | in stock | |
| 27020 | 5 mg | $260 | in stock | |
| 47020 | 25 mg |
$510
|
in stock | |
| 57020 | 50 mg |
$895
|
in stock | |
| 67020 | 100 mg |
$1490
|
in stock |
Cyanine5.5 NHS ester is a reactive dye for the labeling of amino-groups in peptides, proteins, and oligonucleotides, an analog of Cy5.5® NHS ester.
Cy5.5 is a far-red (and near-infrared) emitting dye which is ideal for fluorescence measurements where background fluorescence is a concern. It is also suitable for in vivo NIR imaging experiments.
This reagent can replace NHS esters of Cy5.5® and DyLight 680.
Cy5.5 absorbance and emission spectra
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Amino-reactive BDP FL, a very bright and photostable dye for fluorescein channel.
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General properties
| Appearance: | dark blue to violet solid |
| Molecular weight: | 767.66 |
| CAS number: | 2375105-86-3 |
| Molecular formula: | C44H46N3BF4O4 |
| IUPAC name: | 1H-Benz[e]indolium, 2-[5-(1,3-dihydro-1,1,3-trimethyl-2H-benz[e]indol-2-ylidene)-1,3-pentadien-1-yl]-3-[6-[(2,5-dioxo-1-pyrrolidinyl)oxy]-6-oxohexyl]-1,1-dimethyl- |
| Solubility: | soluble in organic solvents (DMSO, DMF, dichloromethane), practically insoluble in water (< 1 uM, < 1 mg/L) |
| Quality control: | NMR 1H, HPLC-MS (95%) |
| Storage conditions: | Storage: 12 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate. |
| MSDS: | Download |
| Product specifications |
Spectral properties
| Excitation/absorption maximum, nm: | 684 |
| ε, L⋅mol−1⋅cm−1: | 198000 |
| Emission maximum, nm: | 710 |
| Fluorescence quantum yield: | 0.2 |
| CF260: | 0.07 |
| CF280: | 0.03 |
Product citations
- Yun, W.S.; Yang, W.; Shim, M.K.; Song, S.; Choi, J.; Kim, J.; Kim, J.; Moon, Y.; Jo, S.H.; Lim, D.-K.; Kim, K. Accurately controlled tumor temperature with silica-coated gold nanorods for optimal immune checkpoint blockade therapy. Biomaterials Research, 2024. doi: 10.34133/bmr.0024
- Han, G.; Kim, H.; Jang, H.; Kim, E.S.; Kim, S.H.; Yang, Y. Oral TNF-α siRNA delivery via milk-derived exosomes for effective treatment of inflammatory bowel disease. Bioactive Materials, 2024, 34, 138-149. doi: 10.1016/j.bioactmat.2023.12.010
- Wen, H.; Martínez, M.G.; Happonen, E.; Qian, J.; Vallejo, V.G.; Mendazona, H.J.; Jokivarsi, K.; Scaravilli, M.; Latonen, L.; Llop, J.; Lehto, V.-P.; Xu, W. A PEG-assisted membrane coating to prepare biomimetic mesoporous silicon for PET/CT imaging of triple-negative breast cancer. International journal of pharmaceutics, 2024, 652, 123764. doi: 10.1016/j.ijpharm.2023.123764
- Kopp, A.; Kwon, H.; Johnston, C.; Vance, S.; Legg, J.; Galson-Holt, L.; Thurber, G.M. Impact of tissue penetration and albumin binding on design of T cell targeted bispecific agents. Neoplasia, 2024, 48, 100962. doi: 10.1016/j.neo.2023.100962
Cy® is a trademark of Cytiva.
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