DusQ 21 CPG 500

Cat. # Quantity Price Lead time
3151-100mg 100 mg –   in stock
3151-1g 1 g $990 in stock
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DusQ 21 is a quencher for the dyes in far red region of the spectrum. The dye is a xanthene derivative, unlike DusQ 1 or DusQ 2, that are azo dyes. It has a high extinction coefficient, and provides an outstanding quenching efficiency.

The controlled pore glass solid support allows to synthesize oligonucleotides carrying the dye moiety on 3’-terminus.

Usage

Coupling: Standard conditions identical to normal nucleobases.

Deprotection: 2 hours at room temperature using concentrated ammonia.

Absorption spectrum of DusQ 21

Absorption spectrum of DusQ 21

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DusQ 2 NHS ester

DusQ 2 dark quencher with a quenching range from 560 - 670 nm with primary amine reactivity for synthesis of FRET probes. This NHS ester can be coupled to various molecules bearing amino groups.

General properties

Appearance: dark blue beads
Quality control: 1H NMR of bound reagent, coupling testing with HPLC-MS
Storage conditions: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Desiccate. Avoid prolonged exposure to light.
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 656
ε, L⋅mol−1⋅cm−1: 72800

Oligo synthesis details

Pore size, Å: 500
Typical loading, umol/g: 50−80
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