AmdU (5-Azidomethyl-2'-deoxyuridine)
| Cat. # | Quantity | Price | Lead time | Buy this product |
|---|---|---|---|---|
| B1540 | 5 mg | $120 | in stock | |
| D1540 | 25 mg | $255 | in stock | |
| F1540 | 100 mg |
$890
|
in stock |
Azidomethyl-dU (AmdU) is a nucleoside that contains an azide group. The structure of the nucleoside is similar to thymidine, and it is incorporated into nascent DNA by cellular polymerases, similar to EdU.
In contrast to EdU which needs to be further modified with azides in the presence of the copper catalyst, AmdU can also react in the absence of copper catalyst using SPAAC click chemistry with strained cycloalkynes, such as cyclooctynes. This enables the detection of nascent DNA in benign, copper-free conditions.
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A catalyst for click reaction. A stable copper(II) complex which must be converted to monovalent copper(I) in situ using reducing agents. The complex can be used to prepare a reaction buffer of any composition.BDP 650/665 alkyne
BDP 650/665 is a bright borondipyrromethene red-emitting dye. The terminal ethynyl group of BDP 650/665 alkyne can be easily conjugated with various azides using a copper-catalyzed click reaction.
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General properties
| Appearance: | white / off white solid |
| Molecular weight: | 283.24 |
| CAS number: | 59090-48-1 |
| Molecular formula: | C10H13N5O5 |
| IUPAC name: | 5-Azidomethyl-2'-deoxyuridine |
| Solubility: | in water, alcohols, DMSO, DMF |
| Quality control: | NMR 1H, HPLC-MS (95%) |
| Storage conditions: | Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate. |
| MSDS: | Download |
| Product specifications |
Product is offered and sold for research purposes only. Product is not tested for safety and efficacy in food, drug, medical device, cosmetic, no express or implied authorization to use for any other purpose, including, without limitation, in vitro diagnostic purposes, for humans or animals or for commercial purposes.
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