Sulfo-Cyanine5.5 amine
| Cat. # | Quantity | Price | Lead time | Buy this product |
|---|---|---|---|---|
| 173C0 | 1 mg | $110.00 | in stock | |
| 273C0 | 5 mg | $290.00 | in stock | |
| 473C0 | 25 mg |
$690.00
|
in stock | |
| 573C0 | 50 mg |
$1190.00
|
in stock | |
| 673C0 | 100 mg |
$1850.00
|
in stock |
Sulfo-Cyanine5.5 is a water soluble cyanine dye for far red / NIR applications such as in vivo imaging. The dye possesses four sulfonate groups that render it highly hydrophilic and water soluble. As well as other cyanines, sulfo-Cyanine5.5 has an outstanding extinction coefficient that makes it a bright fluorescent label for the far red region.
This is an amine-containing fluorescent dye. The amine group is separated from the fluorophore by a relatively long linker that facilitates conjugation. The aliphatic primary amine group can be coupled with various electrophiles (activated esters, epoxides, etc), and also be used in enzymatic transamination labeling.
Absorption and emission spectra of sulfo-Cyanine5.5 fluorophore
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| Appearance: | dark blue solid |
| Molecular weight: | 1077.41 |
| CAS number: | 2183440-46-0 (potassium salt), 2183440-45-9 |
| Molecular formula: | C46H54K2N4O13S4 |
| IUPAC name: | (E)-4-[(2E,4E)-5-{5-[6-(6-Aminohexylamino)-6-oxohexyl]-3,3-dimethyl-10,12-bis(oxysulfonyl)-5-azatricyclo[7.4.0.02,6]trideca-1,4,6,8,10,12-hexaen-4-yl}-2,4-pentadienylidene]-3,3-dimethyl-5-methyl-5-azatricyclo[7.4.0.02,6]trideca-1,6,8,10,12-pentaene-10,12-disulfonic acid dipotassium salt |
| Solubility: | good in water, DMF, DMSO |
| Quality control: | NMR 1H, HPLC-MS (95%) |
| Storage conditions: | Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate. |
| MSDS: | Download |
| Product specifications |
Spectral properties
| Excitation maximum, nm: | 673 |
| ε, L⋅mol−1⋅cm−1: | 235000 |
| Emission maximum, nm: | 691 |
| CF260: | 0.09 |
| CF280: | 0.11 |
Product citations
- Khatri, S.; Hansen, J.; Mendes, A.C.; Chronakis, I.S.; Hung, S.-C.; Mellins, E.D.; Astakhova, K. Citrullinated Peptide Epitope Targets Therapeutic Nanoparticles to Human Neutrophils. Bioconjugate Chemistry, 2019, 30(10), 2584–2593. doi: 10.1021/acs.bioconjchem.9b00518
- Malinovskaya, Y.; Melnikov, P.; Baklaushev, V.; Gabashvili, A.; Osipova, N.; Mantrov, S.; Ermolenko, Y.; Maksimenko, O.; Gorshkova, M.; Balabanyan, V.; Kreuter, J.; Gelperina, S. Delivery of doxorubicin-loaded PLGA nanoparticles into U87 human glioblastoma cells. International Journal of Pharmaceutics, 2017, 524(1–2), 77–90. doi: 10.1016/j.ijpharm.2017.03.049
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