DBCO STP ester

Cat. # Quantity Price Lead time
2584-5mg 5 mg –   10 days
2584-10mg 10 mg $90.00 in stock
2584-25mg 25 mg $180.00 in stock
2584-100mg 100 mg $450.00 in stock
2584-500mg 500 mg $1700.00 in stock
2584-1g 1 g $3000.00 in stock
2584-5g 5 g please inquire 21 days

Dibenzocyclooctyne sulfotetrafluorophenyl ester (DBCO STP ester) is a water-soluble reagent that can be used for the modification of peptides, antibodies, proteins, and other molecules containing the -NH2 group.

STP esters are hydrolyzed much more slowly than NHS esters, thus allowing efficient biomolecule modification in the aqueous medium.

The dibenzocyclooctyne (DBCO) moiety, which is also known as ADIBO or DIBAC, is the most common substrate for copper-free Click Chemistry reactions that are promoted by ring strain. In this reaction in the presence of a Cu(I) catalyst, DBCO derivatives react with biomolecules functionalized by the azide group to result in stable triazoles.

Customers also purchased with this product

DBCO NHS ester

Azodibenzocyclooctyne (DBCO, ADIBO) reagent for strain promoted copper free Click chemistry (spAAC). The reagent contains an NHS ester function for the attachment of the cyclooctyne to various molecules.

Hexynoic acid STP ester

Alkyne activated ester for the modification of amine groups. STP ester group is an excellent alternative to NHS ester functionality.

Pentynoic acid STP ester

An activated ester for the introduction of alkyne into peptides/proteins.

General properties

Appearance: beige powder
Molecular weight: 569.46
Molecular formula: C26H16NF4O6Sa
Solubility: good in water, DCM, DMF, DMSO
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 12 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Desiccate.
MSDS: Download
Product specifications
Your item has been added. View your cart or proceed to checkout
The count of items is incorrect.