Reactive dyes

Variety at a glance

This interactive fluorescent dye chart helps you select your preferred fluorescent label from our whole portfolio of dyes and reactive groups.

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Near-infrared fluorescent dyes

Bright reactive near-infrared dyes for in vivo imaging and drug discovery ...

Reactive dyes / product groups & items in this category
Reactive dyes for the labeling of biomolecules.
  • BDP 581/591 NHS ester
    NHS ester derivative of BDP 581/591 borondipyrromethene fluorophore for the labeling of proteins, peptides, and other biomolecules. The dye is useful for fluorescence polarization and two-photon experiments, and as a ROS probe.
  • BDP 630/650 X NHS ester
    BDP 630/650 is a borondipyrromethene fluorophore tuned to Cyanine5 excitation and emission channels. The dye is bright and highly photostable. It is useful for fluorescence polarization assays This is an amine-reactive NHS ester derivative.
  • BDP FL NHS ester
    Amino-reactive BDP FL, a very bright and photostable dye for fluorescein channel.
  • BDP R6G NHS ester
    BDP R6G is a borondipyrromethene dye which has absorption and emission spectra similar to R6G.
  • BDP TMR NHS ester
    Amine reactive NHS ester of BDP TMR, bright borondipyrromethene dye for TAMRA channel especially suitable for fluorescence polarization assays.
  • BDP TR NHS ester
    BDP TR is a borondipyrromethene dye for Texas Red channel. A bright and photostable fluorophore with high quantum yield.
  • Coumarin 343 X NHS ester
    Coumarin 343 is a blue emitting dye that can serve as a FRET donor for fluorescein (FAM). This structure features a linker between Coumarin 343 fluorophore, and the functional group. It provides better solubility, and spatial separation between the dye, and the functional group.
  • Cyanine3 NHS ester
    Amine-reactive Cyanine3 dye NHS ester.
  • Cyanine3.5 NHS ester
    Cyanine3.5 dye NHS ester derivative.
  • Cyanine5 NHS ester
    Amine-reactive Cyanine5 activated ester for the labeling of proteins, peptides, and other molecules.
  • Cyanine5.5 NHS ester
    Cyanine5.5 NHS is far-red / near-infrared amine-reactive dye.
  • Cyanine7 NHS ester
    Amine reactive NHS ester of near infrared dye Cyanine7.
  • Cyanine7.5 NHS ester
    Amine reactive NHS ester of NIR fluorescent dye Cyanine7.5.
  • FAM NHS ester, 6-isomer
    Activated N-hydroxysuccinimide ester of fluorescein (FAM), pure 6-isomer.
  • Pyrenebutyric acid NHS ester
    Pyrene NHS ester for the labeling of biomolecules with pyrene residue. Pyrene is a fluorescent proximity probe which forms excimers, and it is also an anchor group for graphite immobilization.
  • ROX NHS ester, pure 6- isomer
    Pure isomer 6-ROX NHS ester for amine labeling.
  • Sulfo-Cyanine3 NHS ester
    Water soluble sulfo-Cyanine3 SE activated ester for amino-biomolecule labeling.
  • Sulfo-Cyanine5 NHS ester
    Water-soluble Cyanine 5 succinimide ester.
  • Sulfo-Cyanine5 bis-NHS ester
    Water soluble amine reactive Cyanine5 dye with two NHS ester groups.
  • Sulfo-Cyanine5.5 NHS ester
    Water soluble, sulfonated, far-red sulfo-Cyanine5.5 dye in the form of NHS ester.
  • Sulfo-Cyanine7 NHS ester
    Sulfo-Cyanine7 NHS ester is a water soluble, near infrared, amine-reactive dye.
  • sulfo-Cyanine7.5 NHS ester
    A water soluble near infrared emitting dye for in vivo imaging applications. Sulfo-Cyanine7.5 is an analog of indocyanine green (ICG) possessing higher emission quantum yield, and containing a linker arm.
  • BDP 581/591 azide
    BDP 581/591 is a relatively hydrophobic borondipyrromethene fluorophore that can be used as a probe for ROS species, or fluorescence polarization tracer. This is an azide derivative for Click chemistry.
  • BDP 630/650 azide
    BDP 630/650 is a bright borondipyrromethene based fluorophore for the far red area of the spectrum. It possesses high extinction coefficient and quantum yield. This is an azide for Click chemistry labeling.
  • BDP FL azide
    BDP FL is a bright and photostable borondipyrromethene dye for fluorescein channel. This is a dye azide for Click Chemistry.
  • BDP R6G azide
    BDP R6G is a high performance borondipyrromethene fluorophore which is tuned to match excitation and emission channels of R6G dye.
  • BDP TMR azide
    Borondipyrromethene dye with azido group. Spectral properties are similar to TAMRA dye. Due to long fluorescence lifetime, BDP TMR is especially useful for fluorescence polarization measurements.
  • BDP TR azide
    BDP TR is a red emitting fluorophore for Texas Red (ROX) channel. This is an azide for copper catalyzed and copper free Click chemistry conjugation.
  • Coumarin 343 X azide
    Coumarin 343 is a blue emitting fluorophore that can serve as a FRET donor for fluorescein (FAM). This azide derivative can be conjugated with alkynes by Click chemistry. An extended linker arm between the fluorophore and the azide group enhances solubility, and provides spatial separation between the dye and the biomolecule.
  • Coumarin 343 azide
    Fluorescent dye azide for Coumarin 343 labeling via Click Chemistry.
  • Cyanine3 azide
    Azide derivative of Cyanine3 fluorescent dye for Click Chemistry.
  • Cyanine3.5 azide
    Cyanine3.5 azide for biomolecule labeling through Click Chemistry.
  • Cyanine5 azide
    Cyanine5 azide is a reagent for Click Chemistry labeling with Cyanine5, a popular fluorescent dye.
  • Cyanine5.5 azide
    Far red / near infrared fluorescent Cyanine5.5 dye derivative for Click Chemistry.
  • Cyanine7 azide
    Near-infrared fluorescent dye for Click Chemistry.
  • Cyanine7.5 azide
    Long-wavelength NIR fluorescent dye azide for Click chemistry.
  • FAM azide, 5-isomer
    FAM (fluorescein) azide for Click chemistry, pure 5-isomer.
  • FAM azide, 6-isomer
    FAM (fluorescein) azide, 6-isomer is a commonly used fluorescent dye azide for Click Chemistry.
  • PEP azide
    PEP (phenylethynylpyrene), polyaromatic hydrocarbon fluorescent dye for Click-Chemistry labeling.
  • Perylene azide
    Perylene is an extremely bright and photostable fluorescent label with green fluorescence.
  • Pyrene azide 1
    Reagent for fluorescent labeling with pyrene polycyclic aromatic hydrocarbon via Click Chemistry.
  • Pyrene azide 2
    Pyrene azide with longer linker, for Click Chemistry.
  • Pyrene azide 3
    Pyrene azide with even longer linker for Click Chemistry.
  • R110 azide, 5- isomer
    R110 dye azide, 5-isomer. R110 fluorescence is similar to FAM. This dye is azide for Click Chemistry.
  • R110 azide, 6- isomer
    Rhodamine 110 (R110) azide for Click chemistry, 6-isomer.
  • ROX azide, 5- isomer
    ROX (aka rhodamine X or rhodamine 101) azide for biomolecule labeling through Click Chemistry.
  • Sulfo-Cyanine3 azide
    Water-soluble sulfo-Cyanine3 dye azide for Click Chemistry.
  • Sulfo-Cyanine5 azide
    Water soluble sulfo-Cyanine5 fluorescent dye azide for Click Chemistry.
  • Sulfo-Cyanine5.5 azide
    Sulfo-Cyanine5.5 azide is a derivative of water soluble far red emitting fluorescent cyanine dye. The azide group can be conjugated by either copper-catalyzed or copper free Click chemistry. The reagent possesses high aqueous solubility and hydrophilicity, and recommended for the labeling of biomolecules in aqueous environment.
  • Sulfo-Cyanine7 azide
    Water-soluble NIR fluorescent dye azide for Click chemistry
  • TAMRA azide, 5-isomer
    TAMRA fluorescent dye azide for Click chemistry.
  • 1-Ethynyl pyrene
    Pyrene is polyaromatic hydrocarbon containing four fused rings. This reagent contains terminal alkyne group for Click Chemistry and other reactions, such as Sonogashira coupling.
  • 3-Ethynyl perylene
    Alkyne derivative of ultra-bright and photostable perylene fluorophore.
  • BDP 581/591 alkyne
    BDP 581/591 is a borondipyrromethene fluorophore which is useful for fluorescence polarization assays, microscopy, and two photon experiments. This alkyne is a derivative for copper-catalyzed Click chemistry.
  • BDP 630/650 alkyne
    Alkyne dye for copper catalyzed Click chemistry, containing borondipyrromethene fluorophore BDP 630/650 for red channel.
  • BDP FL alkyne
    Borondipyrromethene dye alkyne for Click Chemistry. Bright and photostable dye for FAM channel.
  • BDP TMR alkyne
    Borondipyrromethene dye for TAMRA channel, with alkyne group for copper-catalyzed Click Chemistry.
  • BDP TR alkyne
    BDP TR is a fluorophore for Texas Red (ROX) channel. This borondipyrromethene dye is very bright, and resistant to oxidation.
  • Cyanine3 alkyne
    Cyanine3 alkyne is a fluorescent dye alkyne for Click Chemistry.
  • Cyanine5 alkyne
    Cyanine5 alkyne is an alkyne dye for Click Chemistry.
  • Cyanine5.5 alkyne
    Cyanine5.5 alkyne is a NIR (near infrared) dye azide for both copper-catalyzed, and copper-free Click Chemistry.
  • Cyanine7 alkyne
    Cyanine7 alkyne is a near infrared (NIR) dye alkyne for Click chemistry.
  • Cyanine7.5 alkyne
    Reactive near infrared (NIR) dye for Click Chemistry containing a terminal alkyne group.
  • FAM alkyne, 5-isomer
    FAM alkyne, 5-isomer - an alkyne derivative of fluorescein dye for Click Chemistry.
  • FAM alkyne, 6-isomer
    Fluorescein dye alkyne for Click Chemistry, pure 6-isomer.
  • ROX alkyne, 5-isomer
    Rhodamine X (ROX, Rhodamine 101) alkyne derivative for copper catalyzed Click chemistry. ROX is a bright red-emitting dye.
  • Sulfo-Cyanine3 alkyne
    A water soluble dye alkyne for copper-catalyzed Click Chemistry. The fluorophore Sulfo-Cyanine3 is a bright and photostable dye for the Cy3® channel.
  • Sulfo-Cyanine5 alkyne
    Sulfo-Cyanine5 is a water-soluble Cyanine5 dye alkyne for Click chemistry.
  • Sulfo-Cyanine5.5 alkyne
    Alkyne functionalized, water soluble far red/near infrared emitting fluorophore sulfo-Cyanine5.5.
  • Sulfo-Cyanine7 alkyne
    A sulfonated near infrared dye alkyne for copper-catalyzed cycloaddition with azides (CuAAC).
  • TAMRA alkyne, 5-isomer
    Alkyne derivative of TAMRA dye, pure 5-isomer for CuAAC.
  • TAMRA alkyne, 6-isomer
    Terminal alkyne for copper-catalyzed Click chemistry. Tetramethylrhodamine (TAMRA) is a rhodamine dye which is popular in qPCR and other applications. TAMRA is a also a FRET acceptor for FAM.
  • BDP 581/591 maleimide
    Thiol reactive maleimide derivative of BDP 581/591 dye. The fluorophore is useful for a variety of application, including fluorescence polarization assays, and microscopy.
  • BDP 630/650 maleimide
    BDP 630/650 maleimide is a thiol reactive, borondipyrromethene based dye tuned to match the far red channel of Cyanine5 fluorophore.
  • BDP FL maleimide
    BDP FL maleimide is a bright and photostable thiol-reactive dye for protein labeling, an ideal replacement for fluorescein for microscopy.
  • BDP TMR maleimide
    A bright, thiol reactive dye for TAMRA channel. Useful for microscopy and fluorescence polarization assays, among other applications.
  • Cyanine3 maleimide
    Cyanine3 maleimide is a thiol mono reactive dye.
  • Cyanine5 maleimide
    Cyanine5 maleimide reacts with thiols to give dye labeled conjugates.
  • Cyanine5.5 maleimide
    Cyanine5.5 maleimide is a thiol reactive dye for protein labeling.
  • Cyanine7 maleimide
    Cyanine7 maleimide is a sulfhydryl-reactive NIR dye.
  • Cyanine7.5 maleimide
    Cyanine7.5 maleimide is a thiol reactive near infrared dye.
  • FAM maleimide, 6-isomer
    Fluorescein (FAM) maleimide is a thiol reactive dye derived from isomerically pure 6-FAM. Fluorescein is a bright dye that is compatible with various fluorescence measurement instruments.
  • Pyrene maleimide
    Pyrene maleimide derivative for the labeling of thiol groups. Pyrene is a useful excimer-forming proximity probe.
  • Sulfo-Cyanine3 maleimide
    Water soluble thiol-reactive derivative of Sulfo-Cyanine3, a Cy3® analog.
  • Sulfo-Cyanine5 maleimide
    Thiol reactive, water soluble cyanine dye for Cy5® channel.
  • Sulfo-Cyanine7 maleimide
    Water soluble near infrared dye maleimide for the labeling of proteins and peptides.

Dye hydrazides

Dye hydrazides are carbonyl-reactive fluorescent dyes for the labeling of aldehydes and ketones.
  • BDP 630/650 hydrazide
    A carbonyl reactive borondipyrromethene based dye for the red channel (Cyanine5).
  • BDP FL hydrazide
    Bright and photostable, carbonyl reactive borondipyrromethene dye for FAM channel.
  • Cyanine3 hydrazide
    Cyanine3 hydrazide is a carbonyl-reactive dye for Cy3 channel.
  • Cyanine5 Boc-hydrazide
    Protected Cyanine5 hydrazide, a dye with a reactivity for carbonyl groups (aldehydes and ketones) activated by acid.
  • Cyanine5 hydrazide
    Cy5 hydrazide is a reactive dye for aldehydes and ketones. It can be used for the labeling of glycoproteins after periodate oxidation of sugar moieties.
  • Cyanine5.5 hydrazide
    Cyanine5.5 hydrazide is a carbonyl reactive NIR dye which is particularly suitable for the labeling of periodate oxidized glycoproteins, i.e. antibodies.
  • Cyanine7 hydrazide
    Carbonyl reactive NIR fluorophore for the labeling of aldehydes, ketones, including glycoproteins subjected to periodate oxidation.
  • Cyanine7.5 hydrazide
    Near infrared fluorophore functionalized with hydrazide moiety. Reactive against carbonyl compounds, useful for the labeling of saccharides, and antibodies after periodate oxidation.
  • Pyrene hydrazide
    Pyrene hydrazide is a carbonyl reactive dye for the conjugation of pyrene fluorophore with aldehydes and ketones.

Carboxylic acids

Carboxylic acid derivatives of fluorescent dyes. Can be used for the labeling of amines after pre-activation with carbodiimides, and also for Steglich esterification of alcohols.
  • BDP 581/591 carboxylic acid
    BDP 581/591 is a multi purpose fluorophore, that can also be used to probe reactive oxygen species (ROS). This is a carboxylic acid derivative with a free COOH group.
  • BDP 630/650 carboxylic acid
    BDP 630/650 is a bright fluorophore for far red part of the spectrum. This dye is perfect for microscopy and fluorescence polarization assays. This is a carboxylic acid that can be activated for the coupling, or used as a control.
  • BDP FL carboxylic acid
    Borondipyrromethene dye for fluorescein (FAM) channel, free unactivated carboxylic acid useful as a negative control, and for the calibration.
  • BDP R6G carboxylic acid
    Free carboxylic acid derivative of BDP R6G - a borondipyrromethene dye with absorption and emission spectra resembling R6G rhodamine.
  • BDP TMR carboxylic acid
    Borondipyrromethene dye for TMR channel with a non-activated carboxylic acid group.
  • BDP TR carboxylic acid
    BDP TR is a borondipyrromethene dye for ROX/Texas Red channel. This is a carboxy derivative bearing free COOH group for the conjugation with alcohols by Steglich esterification, or for the use in non-conjugated form.
  • Coumarin 343 X carboxylic acid
    Coumarin 343 carboxylic acid. Extended aminohexanoyl linker increases solubility and provides spatial separation between the fluorophore, and the functional group.
  • Cyanine3 carboxylic acid
    Free Cyanine3 carboxylic acid.
  • Cyanine3.5 carboxylic acid
    Unactivated monofunctional Cy3.5 carboxylic acid.
  • Cyanine5 carboxylic acid
    Cyanine5 carboxylic acid, unactivated dye.
  • Cyanine5.5 carboxylic acid
    Cy5.5 unactivated free acid cyanine dye.
  • Cyanine7 carboxylic acid
    Non-reactive, near-infrared fluorescent dye.
  • Cyanine7 dicarboxylic acid
    Cyanine7 dicarboxylic acid is a bifunctional dye molecule possessing two carboxylic acid groups.
  • Cyanine7.5 carboxylic acid
    Cyanine7.5 - unactivated NIR cyanine dye carboxylic acid.
  • Pyrenebutyric acid
    A derivative of pyrene containing a free carboxylic acid function. Pyrene is a polycyclic aromatic hydrocarbon (PAH) which exhibits excimer fluorescence and affinity to graphite.
  • Sulfo-Cyanine3 carboxylic acid
    Sulfo-Cyanine3 free unactivated monofunctional carboxylic acid, water-soluble dye.
  • Sulfo-Cyanine5 carboxylic acid
    Water-soluble Cyanine5 carboxylic acid, non-activated fluorescent dye.
  • Sulfo-Cyanine5.5 carboxylic acid
    Water soluble far red fluorescent dye sulfo-Cyanine5.5, free non-activated carboxylic acid. Useful for the calibration, and as a non-reactive control.
  • Sulfo-Cyanine7 carboxylic acid
    Sulfo-Cy7 carboxylic acid is a non-reactive fluorescent dye which can be used as a NIR (near infrared) marker.
  • Sulfo-Cyanine7.5 carboxylic acid
    Water soluble hydrophilic near infrared fluorescent dye. Carboxylic acid form. Highly hydrophilic due to the presence of four sulfo groups.
  • sulfo-Cyanine7 dicarboxylic acid
    Sulfo-Cyanine7 dicarboxylic acid is a bifunctional dye with two carboxyl groups.

Amino dyes

Fluorescent dyes with free amino groups, for the coupling with various electrophilic compounds like activated esters and epoxides.
  • BDP 630/650 amine
    BDP 630/650 is a far red emitting fluorophore for Cyanine5 channel. This fluorophore is based on BDP (borondipyrromethene) core, which provides high quantum yield and photostability. This is an amine derivative of this dye.
  • BDP FL amine
    Amino derivative of BDP FL dye, borondipyrromethene dye for FAM (fluorescein) 488 nm channel.
  • BDP TMR amine
    BDP TMR amine is an amino dye for TAMRA channel. The dye possesses bright fluorescence and is well suitable for the fluorescence polarization assays.
  • Cyanine3 amine
    Cyanine3 is an fluorophore with free amino group (amino-dye). It can be conjugated with NHS esters, carboxy groups (after activation), and epoxides.
  • Cyanine5 amine
    Cyanine5 amine functionalized dye for the coupling with activated esters and epoxides.
  • Cyanine5.5 amine
    Amino derivative of Cyanine5.5, a far red emitting fluorescent cyanine dye.
  • Cyanine7 amine
    Cy7 amine is a NIR dye with free amine group.
  • Cyanine7.5 amine
    Near infrared dye Cyanine7.5 with free amino group.
  • FAM amine, 5-isomer
    Amino derivative of fluorescein, pure 5-isomer. Contains a linker arm between the aliphatic amine group, and the fluorophore. Useful for the labeling via enzymatic transamination, for the reactions with electrophilic reagents, and for reductive amination.
  • Sulfo-Cyanine3 amine
    Water soluble cyanine dye with bright fluorescence, and high extinction coefficient. Contains an amino group for the conjugation with electrophiles, and enzymatic transamination labeling.
  • Sulfo-Cyanine5 amine
    Sulfonated Cyanine5 amine derivative, for the conjugation with electrophiles, and enzymatic transamination labeling.
  • Sulfo-Cyanine5.5 amine
    Sulfo-Cyanine5.5 is a far red/NIR fluorophore possessing high hydrophilicity and aqueous solubility. The dye displays good brightness in far red region due to outstanding molar extinction coefficient. This is amine derivative which is reactive towards electrophiles. It can also be used for enzymatic transamination labeling.
  • Sulfo-Cyanine7 amine
    Water-soluble NIR dye amine, sulfonated derivative of Cyanine7 dye, for the modification via enzymatical transamination.
  • TAMRA amine, 5-isomer
    TAMRA (tetramethylrhodamine) dye, pure 5-isomer, with an amine group for the conjugation with electrophilic reagents (NHS esters, epoxides, etc).

Tetrazines

Tetrazines are derivatives which react with trans-cyclooctenes, cyclopropenes, and other activated olefines via an inverted electron demand [4+2]-cycloaddition - an example of copper-free Click chemistry reaction.
  • BDP FL tetrazine
    BDP FL tetrazine (methyltetrazine) is a reactive dye for the inverse electron demand Diels-Alder (ied-DA) reaction with trans-cyclooctenes, cyclopropenes, and other strained cycloolefines. BDP FL is a bright and photostable dye for the 488 nm fluorescein (FAM) channel.
  • Sulfo-Cyanine3 tetrazine
    Water soluble sulfo-Cyanine3 dye tetrazine derivative for TCO ligation labeling with trans-cyclooctenes.
  • Sulfo-Cyanine5 tetrazine
    Water soluble Cyanine dye tetrazine derivative for the TCO ligation with trans-cyclooctenes and other strained olefines.

Cycloalkyne dyes

Dyes possessing cycloalkyne moieties for copper free Click chemistry.
  • Cyanine3 DBCO
    Cyanine3 dibenzocyclooctyne (DBCO, or ADIBO) is a cycloalkyne dye derivative for copper free Click chemistry.
  • Cyanine5 DBCO
    Cyanine5 dye with dibenzocyclooctyne (DBCO) functional group for copper free Click chemistry.
  • Cyanine7 DBCO
    NIR fluorescent dye functionalized with cyclooctyne moiety for copper free Click chemistry conjugation with azides.

Miscellaneous dyes

Miscellaneous dye derivatives.
Group tags BDP TR, Microscopy
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