Reactive dyes

Reactive dyes / product groups & items in this category
Reactive dyes for the labeling of biomolecules.
  • BDP 558/568 NHS ester
    BDP 558/568 is a fluorophore for the yellow region of the spectrum. Like other BDP dyes, this fluorophore has high fluorescence quantum yield, brightness, and photostability.
  • BDP 581/591 NHS ester
    NHS ester derivative of BDP 581/591 borondipyrromethene fluorophore for the labeling of proteins, peptides, and other biomolecules. The dye is useful for fluorescence polarization and two-photon experiments, and as a ROS probe.
  • BDP 630/650 X NHS ester
    BDP 630/650 is a borondipyrromethene fluorophore tuned to Cyanine5 excitation and emission channels. The dye is bright and highly photostable. It is useful for fluorescence polarization assays This is an amine-reactive NHS ester derivative.
  • BDP FL NHS ester
    Amino-reactive BDP FL, a very bright and photostable dye for fluorescein channel.
  • BDP R6G NHS ester
    BDP R6G is a borondipyrromethene dye which has absorption and emission spectra similar to R6G.
  • BDP TMR NHS ester
    Amine reactive NHS ester of BDP TMR, bright borondipyrromethene dye for TAMRA channel especially suitable for fluorescence polarization assays.
  • BDP TR NHS ester
    BDP TR is a borondipyrromethene dye for Texas Red channel. A bright and photostable fluorophore with high quantum yield.
  • Coumarin 343 X NHS ester
    Coumarin 343 is a blue emitting dye that can serve as a FRET donor for fluorescein (FAM). This structure features a linker between Coumarin 343 fluorophore, and the functional group. It provides better solubility, and spatial separation between the dye, and the functional group.
  • Cyanine3 NHS ester
    Amine-reactive Cyanine3 dye NHS ester.
  • Cyanine3.5 NHS ester
    Cyanine3.5 dye NHS ester derivative.
  • Cyanine5 NHS ester
    Amine-reactive Cyanine5 activated ester for the labeling of proteins, peptides, and other molecules.
  • Cyanine5.5 NHS ester
    Cyanine5.5 NHS is far-red / near-infrared amine-reactive dye.
  • Cyanine7 NHS ester
    Amine reactive NHS ester of near infrared dye Cyanine7.
  • Cyanine7.5 NHS ester
    Amine reactive NHS ester of NIR fluorescent dye Cyanine7.5.
  • FAM NHS ester, 6-isomer
    Activated N-hydroxysuccinimide ester of fluorescein (FAM), pure 6-isomer.
  • Pyrenebutyric acid NHS ester
    Pyrene NHS ester for the labeling of biomolecules with pyrene residue. Pyrene is a fluorescent proximity probe which forms excimers, and it is also an anchor group for graphite immobilization.
  • ROX NHS ester, pure 6- isomer
    Pure isomer 6-ROX NHS ester for amine labeling.
  • Sulfo-Cyanine3 NHS ester
    Water soluble sulfo-Cyanine3 SE activated ester for amino-biomolecule labeling.
  • Sulfo-Cyanine5 NHS ester
    Water-soluble Cyanine 5 succinimide ester.
  • Sulfo-Cyanine5 alkyne NHS ester
  • Sulfo-Cyanine5 bis-NHS ester
    Water soluble amine reactive Cyanine5 dye with two NHS ester groups.
  • Sulfo-Cyanine5.5 NHS ester
    Water soluble, sulfonated, far-red sulfo-Cyanine5.5 dye in the form of NHS ester.
  • Sulfo-Cyanine7 NHS ester
    Sulfo-Cyanine7 NHS ester is a water soluble, near infrared, amine-reactive dye.
  • Sulfo-Cyanine7.5 NHS ester
    A water soluble near infrared emitting dye for in vivo imaging applications. Sulfo-Cyanine7.5 is an analog of indocyanine green (ICG) possessing higher emission quantum yield, and containing a linker arm.
  • TAMRA NHS ester, 5-isomer
  • TAMRA NHS ester, 6-isomer
  • BDP 581/591 azide
    BDP 581/591 is a relatively hydrophobic borondipyrromethene fluorophore that can be used as a probe for ROS species, or fluorescence polarization tracer. This is an azide derivative for Click chemistry.
  • BDP 630/650 azide
    BDP 630/650 is a bright borondipyrromethene based fluorophore for the far red area of the spectrum. It possesses high extinction coefficient and quantum yield. This is an azide for Click chemistry labeling.
  • BDP FL azide
    BDP FL is a bright and photostable borondipyrromethene dye for fluorescein channel. This is a dye azide for Click Chemistry.
  • BDP R6G azide
    BDP R6G is a high performance borondipyrromethene fluorophore which is tuned to match excitation and emission channels of R6G dye.
  • BDP TMR azide
    Borondipyrromethene dye with azido group. Spectral properties are similar to TAMRA dye. Due to long fluorescence lifetime, BDP TMR is especially useful for fluorescence polarization measurements.
  • BDP TR azide
    BDP TR is a red emitting fluorophore for Texas Red (ROX) channel. This is an azide for copper catalyzed and copper free Click chemistry conjugation.
  • Coumarin 343 X azide
    Coumarin 343 is a blue emitting fluorophore that can serve as a FRET donor for fluorescein (FAM). This azide derivative can be conjugated with alkynes by Click chemistry. An extended linker arm between the fluorophore and the azide group enhances solubility, and provides spatial separation between the dye and the biomolecule.
  • Coumarin 343 azide
    Fluorescent dye azide for Coumarin 343 labeling via Click Chemistry.
  • Cyanine3 azide
    Azide derivative of Cyanine3 fluorescent dye for Click Chemistry.
  • Cyanine3.5 azide
    Cyanine3.5 azide for biomolecule labeling through Click Chemistry.
  • Cyanine5 azide
    Cyanine5 azide is a reagent for Click Chemistry labeling with Cyanine5, a popular fluorescent dye.
  • Cyanine5.5 azide
    Far red / near infrared fluorescent Cyanine5.5 dye derivative for Click Chemistry.
  • Cyanine7 azide
    Near-infrared fluorescent dye for Click Chemistry.
  • Cyanine7.5 azide
    Long-wavelength NIR fluorescent dye azide for Click chemistry.
  • FAM azide, 5-isomer
    FAM (fluorescein) azide for Click chemistry, pure 5-isomer.
  • FAM azide, 6-isomer
    FAM (fluorescein) azide, 6-isomer is a commonly used fluorescent dye azide for Click Chemistry.
  • Fluorescent dye azide kit
    A kit of fluorescent dye azides.
  • JOE azide, 5- isomer
    JOE is a chlorinated fluorescein dye which is often used for HEX channel for oligonucleotides. It is less hydrophobic than HEX. This is an azide derivative for Click chemistry
  • PEP azide
    PEP (phenylethynylpyrene), polyaromatic hydrocarbon fluorescent dye for Click-Chemistry labeling.
  • Perylene azide
    Perylene is an extremely bright and photostable fluorescent label with green fluorescence.
  • Pyrene azide 1
    Reagent for fluorescent labeling with pyrene polycyclic aromatic hydrocarbon via Click Chemistry.
  • Pyrene azide 2
    Pyrene azide with longer linker, for Click Chemistry.
  • Pyrene azide 3
    Pyrene azide with even longer linker for Click Chemistry.
  • R110 azide, 5- isomer
    R110 dye azide, 5-isomer. R110 fluorescence is similar to FAM. This dye is azide for Click Chemistry.
  • R110 azide, 6- isomer
    Rhodamine 110 (R110) azide for Click chemistry, 6-isomer.
  • R6G azide, 5-isomer
    Rhodamine 6G is a xanthene dye that has been used for DNA sequencing and qPCR. This azide derivative is used for the attachment of the dye to DNA and other molecules by means of Click chemistry.
  • R6G azide, 6-isomer
  • ROX azide, 5- isomer
    ROX (aka rhodamine X or rhodamine 101) azide for biomolecule labeling through Click Chemistry.
  • ROX azide, 6-isomer
  • Sulfo-Cyanine3 azide
    Water-soluble sulfo-Cyanine3 dye azide for Click Chemistry.
  • Sulfo-Cyanine5 azide
    Water soluble sulfo-Cyanine5 fluorescent dye azide for Click Chemistry.
  • Sulfo-Cyanine5.5 azide
    Sulfo-Cyanine5.5 azide is a derivative of water soluble far red emitting fluorescent cyanine dye. The azide group can be conjugated by either copper-catalyzed or copper free Click chemistry. The reagent possesses high aqueous solubility and hydrophilicity, and recommended for the labeling of biomolecules in aqueous environment.
  • Sulfo-Cyanine7 azide
    Water-soluble NIR fluorescent dye azide for Click chemistry
  • Sulfo-Cyanine7.5 azide
    Sulfo-Cyanine7.5 is a very hydrophilic and water soluble dye for the near infrared region. The absorption and emission spectra of the dye are similar to indocyanine green (ICG), but sulfo-Cyanine7.5 has a much higher fluorescence quantum yield. The dye is a great choice for near infrared in vivo imaging. This is an azide for Click chemistry.
  • TAMRA azide, 5-isomer
    TAMRA fluorescent dye azide for Click chemistry.
  • TAMRA azide, 6- isomer
  • 1-Ethynyl pyrene
    Pyrene is polyaromatic hydrocarbon containing four fused rings. This reagent contains terminal alkyne group for Click Chemistry and other reactions, such as Sonogashira coupling.
  • 3-Ethynyl perylene
    Alkyne derivative of ultra-bright and photostable perylene fluorophore.
  • BDP 581/591 alkyne
    BDP 581/591 is a borondipyrromethene fluorophore which is useful for fluorescence polarization assays, microscopy, and two photon experiments. This alkyne is a derivative for copper-catalyzed Click chemistry.
  • BDP 630/650 alkyne
    Alkyne dye for copper catalyzed Click chemistry, containing borondipyrromethene fluorophore BDP 630/650 for red channel.
  • BDP FL alkyne
    Borondipyrromethene dye alkyne for Click Chemistry. Bright and photostable dye for FAM channel.
  • BDP R6G alkyne
    Terminal alkyne derivative of BDP R6G dye for Click chemistry. BDP R6G is a borondipyrromethene dye whose absorption and emission spectra are similar to R6G (rhodamine 6G).
  • BDP TMR alkyne
    Borondipyrromethene dye for TAMRA channel, with alkyne group for copper-catalyzed Click Chemistry.
  • BDP TR alkyne
    BDP TR is a fluorophore for Texas Red (ROX) channel. This borondipyrromethene dye is very bright, and resistant to oxidation.
  • Cyanine3 alkyne
    Cyanine3 alkyne is a fluorescent dye alkyne for Click Chemistry.
  • Cyanine5 alkyne
    Cyanine5 alkyne is an alkyne dye for Click Chemistry.
  • Cyanine5.5 alkyne
    Cyanine5.5 alkyne is a NIR (near infrared) dye azide for both copper-catalyzed, and copper-free Click Chemistry.
  • Cyanine7 alkyne
    Cyanine7 alkyne is a near infrared (NIR) dye alkyne for Click chemistry.
  • Cyanine7.5 alkyne
    Reactive near infrared (NIR) dye for Click Chemistry containing a terminal alkyne group.
  • FAM alkyne, 5-isomer
    FAM alkyne, 5-isomer - an alkyne derivative of fluorescein dye for Click Chemistry.
  • FAM alkyne, 6-isomer
    Fluorescein dye alkyne for Click Chemistry, pure 6-isomer.
  • ROX alkyne, 5-isomer
    Rhodamine X (ROX, Rhodamine 101) alkyne derivative for copper catalyzed Click chemistry. ROX is a bright red-emitting dye.
  • Sulfo-Cyanine3 alkyne
    A water soluble dye alkyne for copper-catalyzed Click Chemistry. The fluorophore Sulfo-Cyanine3 is a bright and photostable dye for the Cy3® channel.
  • Sulfo-Cyanine5 alkyne
    Sulfo-Cyanine5 is a water-soluble Cyanine5 dye alkyne for Click chemistry.
  • Sulfo-Cyanine5 alkyne NHS ester
  • Sulfo-Cyanine5.5 alkyne
    Alkyne functionalized, water soluble far red/near infrared emitting fluorophore sulfo-Cyanine5.5.
  • Sulfo-Cyanine7 alkyne
    A sulfonated near infrared dye alkyne for copper-catalyzed cycloaddition with azides (CuAAC).
  • Sulfo-Cyanine7.5 alkyne
    Sulfo-Cyanine7.5 is a near infrared fluorophore similar to indocyanine green (ICG), but possessing higher fluorescence quantum yield. The dye is very hydrophilic and water soluble. The reagent is very useful for the labeling of biomolecules for in vivo imaging. This is an alkyne for copper catalyzed Click chemistry.
  • TAMRA alkyne, 5-isomer
    Alkyne derivative of TAMRA dye, pure 5-isomer for CuAAC.
  • TAMRA alkyne, 6-isomer
    Terminal alkyne for copper-catalyzed Click chemistry. Tetramethylrhodamine (TAMRA) is a rhodamine dye which is popular in qPCR and other applications. TAMRA is a also a FRET acceptor for FAM.
  • sulfo-Cyanine3 DBCO
    Sulfo-Cyanine3 DBCO is a cycloalkyne derivative of water soluble, general purpose fluorophore sulfo-Cyanine3 for Click Chemistry.
  • BDP 581/591 maleimide
    Thiol reactive maleimide derivative of BDP 581/591 dye. The fluorophore is useful for a variety of application, including fluorescence polarization assays, and microscopy.
  • BDP 630/650 maleimide
    BDP 630/650 maleimide is a thiol reactive, borondipyrromethene based dye tuned to match the far red channel of Cyanine5 fluorophore.
  • BDP FL maleimide
    BDP FL maleimide is a bright and photostable thiol-reactive dye for protein labeling, an ideal replacement for fluorescein for microscopy.
  • BDP R6G maleimide
    BDP R6G is a borondipyrromethene dye tuned to R6G (rhodamine 6G) channel. This is a thiol reactive maleimide for the labeling of protein cysteine residues, and other thiols.
  • BDP TMR maleimide
    A bright, thiol reactive dye for TAMRA channel. Useful for microscopy and fluorescence polarization assays, among other applications.
  • Cyanine3 DIGE saturation dye
  • Cyanine3 maleimide
    Cyanine3 maleimide is a thiol mono reactive dye.
  • Cyanine5 maleimide
    Cyanine5 maleimide reacts with thiols to give dye labeled conjugates.
  • Cyanine5.5 maleimide
    Cyanine5.5 maleimide is a thiol reactive dye for protein labeling.
  • Cyanine7 maleimide
    Cyanine7 maleimide is a sulfhydryl-reactive NIR dye.
  • Cyanine7.5 maleimide
    Cyanine7.5 maleimide is a thiol reactive near infrared dye.
  • FAM maleimide, 6-isomer
    Fluorescein (FAM) maleimide is a thiol reactive dye derived from isomerically pure 6-FAM. Fluorescein is a bright dye that is compatible with various fluorescence measurement instruments.
  • Pyrene maleimide
    Pyrene maleimide derivative for the labeling of thiol groups. Pyrene is a useful excimer-forming proximity probe.
  • Sulfo-Cyanine3 maleimide
    Water soluble thiol-reactive derivative of Sulfo-Cyanine3, a Cy3® analog.
  • Sulfo-Cyanine5 maleimide
    Thiol reactive, water soluble cyanine dye for Cy5® channel.
  • Sulfo-Cyanine5.5 maleimide
    Sulfo-Cyanine5.5 is a water-soluble far red emitting dye. This is a thiol reactive maleimide derivative of sulfo-Cyanine5.5. It is recommended for the labeling of sensitive proteins.
  • Sulfo-Cyanine7 maleimide
    Water soluble near infrared dye maleimide for the labeling of proteins and peptides.

Dye hydrazides

Dye hydrazides are carbonyl-reactive fluorescent dyes for the labeling of aldehydes and ketones.
  • BDP 581/591 hydrazide
    BDP 581/591 is a multi-purpose dye with bright emission. This is a hydrazide dye for the conjugation with aldehydes and ketones.
  • BDP 630/650 hydrazide
    A carbonyl reactive borondipyrromethene based dye for the red channel (Cyanine5).
  • BDP FL hydrazide
    Bright and photostable, carbonyl reactive borondipyrromethene dye for FAM channel.
  • Cyanine3 hydrazide
    Cyanine3 hydrazide is a carbonyl-reactive dye for Cy3 channel.
  • Cyanine5 Boc-hydrazide
    Protected Cyanine5 hydrazide, a dye with a reactivity for carbonyl groups (aldehydes and ketones) activated by acid.
  • Cyanine5 hydrazide
    Cy5 hydrazide is a reactive dye for aldehydes and ketones. It can be used for the labeling of glycoproteins after periodate oxidation of sugar moieties.
  • Cyanine5.5 hydrazide
    Cyanine5.5 hydrazide is a carbonyl reactive NIR dye which is particularly suitable for the labeling of periodate oxidized glycoproteins, i.e. antibodies.
  • Cyanine7 hydrazide
    Carbonyl reactive NIR fluorophore for the labeling of aldehydes, ketones, including glycoproteins subjected to periodate oxidation.
  • Cyanine7.5 hydrazide
    Near infrared fluorophore functionalized with hydrazide moiety. Reactive against carbonyl compounds, useful for the labeling of saccharides, and antibodies after periodate oxidation.
  • FAM hydrazide, 5-isomer
    FAM hydrazide is a carbonyl reactive fluorescein derivative. Pure 5-isomer. Can label oxidized proteins, saccharides, and many small molecules with carbonyl groups.
  • Pyrene hydrazide
    Pyrene hydrazide is a carbonyl reactive dye for the conjugation of pyrene fluorophore with aldehydes and ketones.
  • sulfo-Cyanine3 hydrazide

Carboxylic acids

Carboxylic acid derivatives of fluorescent dyes. Can be used for the labeling of amines after pre-activation with carbodiimides, and also for Steglich esterification of alcohols.
  • BDP 581/591 amine
    BDP 581/591 fluorophore derivative with free amine group for the conjugation with electrophilic reagents, and enzymatic transamination.
  • BDP 630/650 amine
    BDP 630/650 is a far red emitting fluorophore for Cyanine5 channel. This fluorophore is based on BDP (borondipyrromethene) core, which provides high quantum yield and photostability. This is an amine derivative of this dye.
  • BDP FL amine
    Amino derivative of BDP FL dye, borondipyrromethene dye for FAM (fluorescein) 488 nm channel.
  • BDP R6G amine
    Amine derivative of BDP R6G, borondipyrromethene dye matching Rhodamine 6G (R6G) channel. The terminal aliphatic amine group can be conjugated with various electrophiles.
  • BDP TMR amine
    BDP TMR amine is an amino dye for TAMRA channel. The dye possesses bright fluorescence and is well suitable for the fluorescence polarization assays.
  • BDP TR Amine
    BDP TR borondipyrromethene dye with a free amine group for the conjugation with electrophilic reagents and enzymatic transamination reaction. BDP TR is a bright dye for ROX channel.
  • Cyanine3 amine
    Cyanine3 is an fluorophore with free amino group (amino-dye). It can be conjugated with NHS esters, carboxy groups (after activation), and epoxides.
  • Cyanine5 amine
    Cyanine5 amine functionalized dye for the coupling with activated esters and epoxides.
  • Cyanine5.5 amine
    Amino derivative of Cyanine5.5, a far red emitting fluorescent cyanine dye.
  • Cyanine7 amine
    Cy7 amine is a NIR dye with free amine group.
  • Cyanine7.5 amine
    Near infrared dye Cyanine7.5 with free amino group.
  • FAM amine, 5-isomer
    Amino derivative of fluorescein, pure 5-isomer. Contains a linker arm between the aliphatic amine group, and the fluorophore. Useful for the labeling via enzymatic transamination, for the reactions with electrophilic reagents, and for reductive amination.
  • FAM amine, 6-isomer
    Amine derivative of fluorescein (FAM) fluorophore, pure 6-isomer, for the enzymatic transamination labeling, reactions with electrophilic reagents, and reductive amination.
  • Sulfo-Cyanine3 amine
    Water soluble cyanine dye with bright fluorescence, and high extinction coefficient. Contains an amino group for the conjugation with electrophiles, and enzymatic transamination labeling.
  • Sulfo-Cyanine5 amine
    Sulfonated Cyanine5 amine derivative, for the conjugation with electrophiles, and enzymatic transamination labeling.
  • Sulfo-Cyanine5.5 amine
    Sulfo-Cyanine5.5 is a far red/NIR fluorophore possessing high hydrophilicity and aqueous solubility. The dye displays good brightness in far red region due to outstanding molar extinction coefficient. This is amine derivative which is reactive towards electrophiles. It can also be used for enzymatic transamination labeling.
  • Sulfo-Cyanine7 amine
    Water-soluble NIR dye amine, sulfonated derivative of Cyanine7 dye, for the modification via enzymatical transamination.
  • TAMRA amine, 5-isomer
    TAMRA (tetramethylrhodamine) dye, pure 5-isomer, with an amine group for the conjugation with electrophilic reagents (NHS esters, epoxides, etc).

Tetrazines

Tetrazines are derivatives which react with trans-cyclooctenes, cyclopropenes, and other activated olefines via an inverted electron demand [4+2]-cycloaddition - an example of copper-free Click chemistry reaction.
  • BDP FL tetrazine
    BDP FL tetrazine (methyltetrazine) is a reactive dye for the inverse electron demand Diels-Alder (ied-DA) reaction with trans-cyclooctenes, cyclopropenes, and other strained cycloolefines. BDP FL is a bright and photostable dye for the 488 nm fluorescein (FAM) channel.
  • Cyanine3 tetrazine
    Tetrazine derivative of Cyanine3 fluorophore. Tetrazines react extremely quickly with strained alkenes (such as trans-cyclooctenes, cyclopropenes), and some strained alkynes.
  • Cyanine5 tetrazine
    Cyanine5 is a universal red emitting dye with very high extinction coefficient, and good quantum yield. This tetrazine derivative reacts very quickly with trans-cyclooctenes and cyclopropenes with the formation of stable conjugates.
  • Cyanine5.5 tetrazine
    A compound containing Cyanine5.5 fluorophore, a far red emitting dye, and tetrazine fragment for the conjugation with trans-cyclooctenes / cyclopropenes via TCO ligation.
  • Cyanine7 tetrazine
    Near infrared Cyanine7 dye derivative containing tetrazine group for TCO ligation.
  • Cyanine7.5 tetrazine
    Cyanine7.5 is a NIR fluorescent dye with absorption and emission spectra similar to ICG (indocyanine green), but possessing a higher fluorescence quantum yield. This derivative is a tetrazine derivative for the TCO ligation reaction.
  • FAM tetrazine, 6-isomer
  • Sulfo-Cyanine3 tetrazine
    Water soluble sulfo-Cyanine3 dye tetrazine derivative for TCO ligation labeling with trans-cyclooctenes.
  • Sulfo-Cyanine5 tetrazine
    Water soluble Cyanine dye tetrazine derivative for TCO ligation with trans-cyclooctenes and other strained olefines.

Cycloalkyne dyes

Dyes possessing cycloalkyne moieties for copper free Click chemistry.
  • Cyanine3 DBCO
    Cyanine3 dibenzocyclooctyne (DBCO, or ADIBO) is a cycloalkyne dye derivative for copper free Click chemistry.
  • Cyanine5 DBCO
    Cyanine5 dye with dibenzocyclooctyne (DBCO) functional group for copper free Click chemistry.
  • Cyanine7 DBCO
    NIR fluorescent dye functionalized with cyclooctyne moiety for copper free Click chemistry conjugation with azides.

Miscellaneous dyes

Miscellaneous dye derivatives.
Group tags BDP TR, Microscopy
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