Click Chemistry reagents

Click Chemistry reagents / product groups & items in this category
Reagents for Click Chemistry labeling and conjugation, non-fluorescent azides, alkynes.

Non-fluorescent azides

Various non-fluorescent azides for Click Chemistry. Fluorescent azides are listed under Reactive dyes category.
  • AmdU (5-azidomethyl-2'-deoxyuridine)
    Azidomethyldeoxyuridine (AmdU) is an azide containing nucleoside that is incorporated into nascent DNA by cellular polymerases. The azide groups attached to DNA this way can be subsequently modified with alkynes or cycloalkynes via copper-catalyzed or strain promoted Click chemistry.
  • Azidobutyric acid NHS ester
    Activated ester for azido labeling of peptides and proteins.
  • Biotin azide
    Biotin azide is a reagent for click chemistry labeling with biotin, a well-known affinity probe.

Non-fluorescent alkynes

Various non-fluorescent alkynes for copper-catalyzed Click Chemistry. Fluorescent dye alkynes are listed under 'Reactive dyes' category.
  • Alkyne NHS ester (hexynoic acid NHS ester)
    Alkyne NHS ester for the labeling of biomolecules with alkyne group for Copper catalyzed Click chemistry.
  • Alkyne hydrazide
    Bifunctional reagent containing alkyne group and hydrazide function. It reacts with aldehydes and ketones. Alkyne group can then be coupled with various azides via CuAAC reaction.
  • Alkyne maleimide
    Maleimide reagent for the attachment of alkyne functional group to proteins, peptides, and other molecules bearing SH (thiol) groups, including cysteine residues.
  • Biotin alkyne
    Biotin alkyne is a reactive affinity label which can be attached to biomolecules via Click Chemistry.
  • DBCO NHS ester
    Azodibenzocyclooctyne (DBCO, ADIBO) reagent for strain promoted copper free Click chemistry (spAAC). The reagent contains an NHS ester function for the attachment of the cyclooctyne to various molecules.
  • EdU (5-ethynyl-2'-deoxyuridine)
    EdU is a nucleoside which is incorporated into replicated DNA by cellular enzymes. After it, DNA contained in the cells can be developed by Click chemistry reaction with fluorescent dye azides to reveal cell proliferation.
  • Pentynoic acid STP ester
    An activated ester for the introduction of alkyne into peptides/proteins.
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