Cell biology reagents

Cell biology reagents / product groups & items in this category
Dyes and reagents for cell biology: cell markers and indicators, substances for metabolic labeling, inhibitors, etc.

Nuclear stains

Cell-membrane permeable and impermeant DNA dyes for specific staining nuclei in live or fixed cells.
Group tags Microscopy, Super-resolution imaging, Flow cytometry, Cell viability and apoptosis, Nuclei

Plasma membrane stains

Lipophilic dyes for plasma membrane staining and visualization of cell boundaries and morphology.
Group tags Near infrared (NIR) imaging, Microscopy, Cell proliferation, Neuroscience, Flow cytometry, Cell membrane

Organelle stains

Reagents and kits for detecting specific cell organelles and structures in live and fixed cells.
Group tags Near infrared (NIR) imaging, Microscopy, Mitochondria, Lipid bodies, Neuroscience, Flow cytometry, Cell membrane, Synaptic vesicles, Cell viability and apoptosis, Golgi apparatus, Membrane potential measurement
  • LumiTracker Lyso Green
    Green-fluorescent dye for visualization of lysosomes in living cells and other cell organelles with a low pH. Analog of LysoTracker™ Green DND-26.
  • LumiTracker Lyso Red
    Red-fluorescent reagent for labeling and tracking lysosomes and other acidic organelles with low internal pH in live cells. Analog of LysoTracker™ Red DND-99.
  • BDP 493/503 lipid stain
    BDP 493/503 is a lipophilic green fluorescent dye for the staining and tracing of cell membranes, lipids, and oils.
  • BDP 505/515 lipid stain
    BDP 505/515 is a lipid staining dye for cell membranes. It has a high fluorescence quantum yield, and is very photostable.
  • BDP 630/650 lipid stain
    Far-red fluorescent dye BDP 630/650 for staining of lipids and and other lipophilic compounds.
  • BDP 650/665 lipid stain
    Hydrophobic borondipyrromethene dye BDP 650/665 for staining of lipids and lipophilic compounds.
  • BDP FL ceramide
    BDP FL ceramide is fluorescent lipid for the visualization of Golgi apparatus.
  • BDP TMR ceramide
    Sphingosine derivative of BDP TMR for the visualization of Golgi apparatus membranes of live cells.
  • BDP TR ceramide
    Conjugate of BDP TR fluorescent dye with sphingosine for the visualization of membranes of Golgi apparatus.
  • LumiTrace BDP TR methyl ester
    BDP TR methyl ester is a lipophilic counterstain for GFP (5 mM solution in DMSO). Сell-permeable dye that stains mitochondria and endomembranous organelles, but not plasma membrane.
  • LumiTracker Mito JC-1
    The cationic carbocyanine dye that is widely used as an indicator of mitochondrial membrane potential to study apoptosis and monitor the health of mitochondria.
  • LumiTracker Mito Orange CMTMRos
    Сell-permeant, cationic, orange-fluorescent dye for staining active mitochondria in living cells in a potential-dependent manner. The stain is compatible with aldehyde fixation.
  • LumiTracker Mito Red CMXRos
    Сell-permeant, cationic, red-fluorescent dye for staining active mitochondria in living cells in a potential-dependent manner. The stain is compatible with aldehyde fixation.
  • LumiTracker Mito Red FM
    Сell-permeant, cationic, red-fluorescent dye for staining active mitochondria in living cells in a potential-dependent manner.
  • LumiTracker Mito Rhodamine 123
    Rhodamine 123 is a cell-permeant, green-fluorescent dye that stains mitochondria in living cells in a membrane potential-dependent manner.
  • LumiTracker Mito TMRE
    Tetramethylrhodamine ethyl ester (TMRE) is an orange-red fluorescent dye for staining active mitochondria and quantitate mitochondrial membrane potential in live cells.
  • SynaptoProbe Green
    SynaptoProbe Green is an analog of FM®1-43, a widely used green fluorescent dye for staining synaptic vesicles and studying synaptic activity in the synapses or neuromuscular junctions.

Cell tracing and tracking

Our dyes for anterograde and retrograde tracing of living and fixed cells and cell tracking.
Group tags Near infrared (NIR) imaging, Microscopy, NHS esters, Biotinylation, Cell proliferation, Neuroscience, Flow cytometry, Cell membrane

Cell viability indicators

Reagents and ready-to-use kits for studying cell viability and apoptosis by flow cytometry and microscopy.
Group tags Microscopy, Mitochondria, Flow cytometry, Cell viability and apoptosis, Membrane potential measurement

ROS indicators

Cell permeant fluorogenic dyes for detection of reactive oxygen species (ROS) in live cells by flow cytometry, microscopy, or fluorimetry.
Group tags Microscopy, ROS sensing, Flow cytometry

Ion and pH indicators

Small fluorogenic molecules for indicating specific ions inside cells in vivo. Cell permeant indicators for Ca-, Fe-ions, pH, and others.
Group tags Microscopy, Fluorometry, Neuroscience, Flow cytometry
  • Fluo-4 AM, green fluorescent calcium indicator
    Fluo-4 AM is a cell-permeable calcium ion indicator that is metabolized by intracellular esterase, leading to a bright green fluorescent signal upon calcium ion binding. Fluo-4 AM is well suited for fluorometric and imaging applications.
  • Fluo-8 AM, green fluorescent calcium indicator
    Fluo-8 AM is a cell-permeable calcium ion indicator that is metabolized by intracellular esterase, leading to a bright green fluorescent signal upon calcium ion binding. Fluo-8 AM has brighter fluorescence than Fluo-4 AM and is excellent for applications where dye concentration must be minimized.
  • HMRhoNox-M, Fe(II)-selective fluorescent probe
    Fe(II)-responsive turn-on fluorescent probe for monitoring fluctuations of endogenous labile iron in living cells.

Cell type-specific markers

Small-molecule fluorescent markers for different types of cells. A fast and well-permeant to live cells and tissues alternative to antibody labeling.
Group tags Microscopy, Neuroscience, Flow cytometry
  • LumiCell CDr20 Microglia Stain
    CDr20 is a turn-on fluorescent chemical probe for specific labeling and visualizing microglia in cell cultures and live brains.
  • LumiCell Reticulocyte Stain
    LumiCell Reticulocyte Stain is a ready-to-use Thiazole Orange solution for determining a percentage of reticulocytes in human peripheral blood with microscopy and flow cytometry.

Immunofluorescence

Reagents for immunofluorescence applications: fluorescently labeled derivatives of tyramide, biotin, and streptavidin for Western Blotting, immunoassay, immunochemistry, and in situ hybridization.
Group tags Microscopy, AF 488, sulfo-Cyanine7, AF 594, Super-resolution imaging, sulfo-Cyanine5, Flow cytometry, sulfo-Cyanine3, sulfo-Cyanine5.5
  • AF 488 streptavidin
    AF 488 conjugate of streptavidin, a high-affinity biotin-binding protein, for immunofluorescence, western blots, microplate assays, and other applications use.
  • AF 488 tyramide
    A tyramide derivative of AF 488, a green fluorescent reagent widely used for tyramide signal amplification (TSA) in IHC, ICC, and FISH.
  • AF 594 streptavidin
    AF 594 conjugate of streptavidin, a high-affinity biotin-binding protein, for immunofluorescence, western blots, microplate assays, and other applications use.
  • AF 594 tyramide
    A tyramide derivative of AF 594, a red fluorescent reagent widely used for tyramide signal amplification (TSA) in IHC, ICC, and FISH.
  • sulfo-Cyanine3 streptavidin
    sulfo-Cyanine3 conjugate of streptavidin, a high-affinity biotin-binding protein, for immunofluorescence, western blots, microplate assays, and other applications use.
  • sulfo-Cyanine3 tyramide
    A tyramide derivative of sulfo-Cyanine3, an orange fluorescent reagent widely used for tyramide signal amplification (TSA) in IHC, ICC, and FISH.
  • sulfo-Cyanine3-PEG3-biotin
    Conjugate of hydrophilic sulfo-Cyanine3 dye with biotin, affinity label for avidin/streptavidin.
  • sulfo-Cyanine5 streptavidin
    sulfo-Cyanine5 conjugate of streptavidin, a high-affinity biotin-binding protein, for immunofluorescence, western blots, microplate assays, and other applications use.
  • sulfo-Cyanine5 tyramide
    A tyramide derivative of sulfo-Cyanine5, a far-red fluorescent reagent widely used for tyramide signal amplification (TSA) in IHC, ICC, and FISH.
  • sulfo-Cyanine5-PEG3-biotin
    Biotin conjugate of the far-red fluorescent sulfo-Cyanine5 dye.
  • sulfo-Cyanine5.5 tyramide
    A tyramide derivative of sulfo-Cyanine5.5, a far-red fluorescent reagent widely used for tyramide signal amplification (TSA) in IHC, ICC, and FISH.
  • sulfo-Cyanine7 tyramide
    A tyramide derivative of sulfo-Cyanine7, a near-infrared fluorescent reagent widely used for tyramide signal amplification (TSA) in IHC, ICC, and FISH.

Metabolic labeling

Reagents for metabolic in vivo labeling of cells and whole organisms.
Group tags PET/CT imaging, Copper-free click chemistry, Alkynes, Cell proliferation, Click chemistry, Azides
  • Ac4GlcNAz (N-Azidoacetylglucosamine-tetraacylated)
    An azide-functionalized monosaccharide for metabolic labeling and studying the cellular trafficking of labeled proteins and proteomic analysis.
  • Ac4GalNAz (N-Azidoacetylgalactosamine-tetraacylated)
    An azide-functionalized monosaccharide for metabolic labeling and studying the cellular trafficking of labeled proteins and proteomic analysis.
  • Ac4ManNAz (N-Azidoacetylmannosamine-tetraacylated)
    An azide-functionalized monosaccharide for metabolic labeling and studying the cellular trafficking of labeled proteins and proteomic analysis.
  • AmdU (5-Azidomethyl-2'-deoxyuridine)
    Azidomethyldeoxyuridine (AmdU) is an azide-contained nucleoside that is incorporated into nascent DNA by cellular polymerases. The azide groups attached to DNA this way can be subsequently modified with alkynes or cycloalkynes via copper-catalyzed or strain-promoted click reaction.
  • BrdU (5-Bromo-2′-deoxyuridine)
    BrdU is a synthetic analog of thymidine for studying de novo DNA synthesis and cell proliferation.
  • EU (5-Ethynyl-uridine)
    Uridine alkyne derivative for monitoring and investigation of RNA transcription in cells.
  • EdU (5-Ethynyl-2'-deoxyuridine)
    EdU is a nucleoside that is incorporated into replicated DNA by cellular enzymes. After it, DNA contained in the cells can be developed by click chemistry reaction with fluorescent dye azides to reveal cell proliferation.
  • F-ara-EdU (2’-Deoxy-2’-fluoro-5-ethynyluridine)
    F-ara-EdU is a synthetic analog of thymidine used to study de novo DNA synthesis and cell proliferation. It is a less cytotoxic alternative for BrdU and EdU.
  • HPG (L-Homopropargylglycine)
    Noncanonical amino acid analog of methionine with a terminal alkyne moiety for nascent protein synthesis detection.
  • TE-L-Tyrosine (FET-precursor)
    O-Tosyloxyethyl-N-trityl-tyrosine tert-butyl ester (also known as TET) is a precursor for O-(2-[18F]fluoroethyl)-L-tyrosine (FET) - a widely used F18-labeled amino acid tracer for positron emission tomography and computed tomography (PET/CT).
  • VU (5-Vinyl-uridine)
    Uridine derivative with a terminal alkene group for monitoring and investigating cell RNA transcription.
  • VdU (5-Vinyl-2'-deoxyuridine)
    VdU is a synthetic analog of thymidine for studying de novo DNA synthesis and cell proliferation.

Mounting media for microscopy

Fluorescence mounting media for microscopy applications.
Group tags Microscopy

Inhibitors and activators

Group tags Neuroscience, Cell viability and apoptosis
  • Annexin V, His Tag
    Recombinant Human Annexin V for producing fluorescent Annexin V conjugates and inhibition of the procoagulant and proinflammatory activities of the apoptotic cells.
  • DREADD agonist 21 dihydrochloride
    An agonist for selective activation of hM3Dq (excitatory) and hM4Di (inhibitory) DREADDs. A widely used chemogenetic tool for remotely controlling neuronal activity.
  • Vacuolin-1
    Cell-permeable inhibitor of calcium-dependent lysosomal exocytosis.
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