sulfo-Cyanine7 NHS ester

Cat. # Quantity Price Lead time
15320 1 mg $125.00 in stock
25320 5 mg $325.00 in stock
45320 25 mg $850.00 in stock
55320 50 mg $1490.00 in stock
65320 100 mg $1990.00 in stock

Water-soluble near-infrared dye sulfo-Cyanine7, an amine-reactive succinimide ester.

sulfo-Cyanine7 is an improved analog of Cy7® fluorophore with quantum yield improved by 20%, and higher photostability. This fluorescent dye is especially useful for NIR imaging.

Near-infrared fluorescent imaging takes advantage of the transparency of biological tissues at a particular range of wavelengths. The method is non-destructive and allows to monitor of the distribution of various labeled molecules in live organisms.

sulfo-Cyanine7 NHS ester reagent allows to prepare sulfo-Cyanine7-labeled biomolecules, such as proteins, with ease. Dye-labeled molecules can be subsequently used for various research and drug design-related experiments.

This reagent has high water solubility and is especially useful for labeling delicate proteins and proteins prone to denaturation. Non-sulfonated Cyanine7 NHS ester soluble in the organic phase is also available.

sulfo-Cyanine7 absorbance and emission spectra

sulfo-Cyanine7 absorbance and emission spectra

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General properties

Appearance: dark green powder
Molecular weight: 844.05
CAS number: 1603861-95-5 (potassium salt); 1604244-45-2 (inner salt); 477908-53-5 (N-Ethyl)
Molecular formula: C41H46N3KO10S2
Solubility: good in water, DMF, DMSO
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 12 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 750
ε, L⋅mol−1⋅cm−1: 240600
Emission maximum, nm: 773
Fluorescence quantum yield: 0.24
CF260: 0.04
CF280: 0.04

Product citations

  1. Feng, X.A.; Ness, K.M.; Liu, C.; Ahmed, I.; Bowman, G.D.; Ha, T.; Wu, C. GAGA Factor Overcomes 1D Diffusion Barrier by 3D Diffusion in Search of Nucleosomal Targets. bioRxiv, 2023, preprint. doi: 10.1101/2023.07.14.549009
  2. Sandberg, E.; Piguet, J.; Kostiv, U.; Baryshnikov, G.; Liu, H.; Widengren, J. Photoisomerization of Heptamethine Cyanine Dyes Results in Red-Emissive Species: Implications for Near-IR, Single-Molecule, and Super-Resolution Fluorescence Spectroscopy and Imaging. J Phys Chem B, 2023, 127(14), 3208–3222. doi: 10.1021/acs.jpcb.2c08016
  3. Birnbaum, L.A.; Sullivan, E.C.; Do, P.; Uricoli, B.; Raikar, S.S.; Porter, C.C.; Henry, C.J.; Dreaden, E.C. Multicolor Light-Induced Immune Activation via Polymer Photocaged Cytokines. Biomacromolecules, 2023, 24(3), 1164-1172. doi: 10.1021/acs.biomac.2c01207
  4. Hao, L.; Zhao, R.T.; Welch, N.L.; Tan, E.K.W.; Zhong, Q.; Harzallah, N.S.; Ngambenjawong, C.; Ko, H.; Fleming, H.E.; Sabeti, P.C.; Bhatia, S.N. CRISPR-Cas-amplified urinary biomarkers for multiplexed and portable cancer diagnostics. Nature Nanotechnology, 2023, 18, 798-807. doi: 10.1038/s41565-023-01372-9
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