Cyanine7.5 NHS ester
Cat. # | Quantity | Price | Lead time | Buy this product |
---|---|---|---|---|
16020 | 1 mg | $125.00 | in stock | |
26020 | 5 mg | $260.00 | in stock | |
46020 | 25 mg | $510.00 | in stock | |
56020 | 50 mg | $895.00 | in stock | |
66020 | 100 mg | $1490.00 | in stock |
Cyanine7.5 is a NIR dye with very long-wave emission. This product is amine-reactive derivative of this fluorophore.
Near infrared radiation readily penetrates tissues and can be used for imaging applications in vivo.
This product can be used for the labeling of various biomolecules containing amine groups, such as proteins and peptides, to track their distribution in organism in vivo by NIR imaging.
Increased rigidity of central polymethyne moiety allows to increase quantum yield by 20% compared to parent structure of Cy7.5® NHS.
Cy7.5 absorbance and emission spectra
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DBCO NHS ester
Azodibenzocyclooctyne (DBCO, ADIBO) reagent for strain-promoted copper-free click chemistry (SPAAC). The reagent contains an NHS ester function for the attachment of the cyclooctyne to various molecules.General properties
Appearance: | green powder |
Mass spec M+ increment: | 630.4 |
Molecular weight: | 833.76 |
CAS number: | 2708152-94-5 |
Molecular formula: | C49H52N3BF4O4 |
IUPAC name: | 1H-Benz[e]indolium, 2-[2-[3-[2-(1,3-dihydro-1,1,3-trimethyl-2H-benz[e]indol-2-ylidene)ethylidene]-1-cyclohexen-1-yl]ethenyl]-3-[6-[(2,5-dioxo-1-pyrrolidinyl)oxy]-6-oxohexyl]-1,1-dimethyl- |
Solubility: | soluble in organic solvents (DMSO, DMF, dichloromethane), low solubility in water |
Quality control: | NMR 1H, HPLC-MS (95%) |
Storage conditions: | Storage: 12 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate. |
MSDS: | Download |
Product specifications |
Spectral properties
Excitation/absorption maximum, nm: | 788 |
ε, L⋅mol−1⋅cm−1: | 223000 |
Emission maximum, nm: | 808 |
Fluorescence quantum yield: | 0.10 |
Product citations
- Nie, Q.; Li, C.; Wang, Y.; Hu, Y.; Pu, W.; Zhang, Q.; Cai, J.; Lin, Y.; Li, G.; Wang, C.; Li, L.; Dou, Y.; Zhang, J. Pathologically Triggered in Situ Aggregation of Nanoparticles for Inflammation-Targeting Amplification and Therapeutic Potentiation. Acta Pharmaceutica Sinica B, 2023, 13(1), 390–409. doi: 10.1016/j.apsb.2022.07.013
- Sreekanth, K.V.; Perumal, J.; Dinish, U.S.; Prabhathan, P.; Liu, Y.; Singh, R.; Olivo, M.; Teng, J. Tunable Tamm plasmon cavity as a scalable biosensing platform for surface enhanced resonance Raman spectroscopy. Nature Communications, 2023, 14, 7085. doi: 10.1038/s41467-023-42854-7
- Tang, M.; Chen, B.; Xia, H.; Pan, M.; Zhao, R.; Zhou, J.; Yin, Q.; Wan, F.; Yan, Y.; Fu, C.; Zhong, L.; Zhang, Q.; Wang, Y. pH-gated nanoparticles selectively regulate lysosomal function of tumour-associated macrophages for cancer immunotherapy. Nature Communications, 2023, 14, 5888. doi: 10.1038/s41467-023-41592-0
- Yan, Y.; Chen, B.; Yin, Q.; Wang, Z.; Yang, Y.; Wan, F.; Wang, Y.; Tang, M.; Xia, H.; Chen, M.; Liu, J.; Wang, S.; Zhang, Q.; Wang, Y. Dissecting Extracellular and Intracellular Distribution of Nanoparticles and Their Contribution to Therapeutic Response by Monochromatic Ratiometric Imaging. Nat Commun, 2022, 13(1), 2004. doi: 10.1038/s41467-022-29679-6
Cy® is a trademark of GE Healthcare.
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