Cy7 NHS ester

Lot No	Quantity	Price
15020	1 mg	$ 110.00
25020	5 mg	$ 210.00
45020	25 mg	$ 410.00
55020	50 mg	$ 695.00
65020	100 mg	$ 1190.00

Amine reactive Cy7, near infrared (NIR) fluorescent dye.

NIR fluorophores can be used to take advantage of near infrared window of biological tissues. Highly increased transparency of tissues in this spectral region allows to carry out in vivo imaging.

This reagent can be utilized to produce Cy7-labeled biomolecules, which can be subsequently used in various research and drug design related experiments.

This particular Cy7 structure features rigidized design of central polymethyne chain. This molecular reinforcement allows to increase quantum yield by 20% compared with parent structure, increasing fluorescence brightness.

This reagent requires organic co-solvent for the labeling (please see Recommended Protocols section below). Water-soluble Cy7 NHS ester is also available, and recommended for protein labeling.

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General properties
Appearance:	dark green powder
Molar weight:	682.29
Solubility:	Good in organic solvents (DCM, chloroform, DMF, DMSO, MeCN, alcohols), poor in water
Mass spec M+ increase:	531.3
Spectral properties
Cy7 excitation maximum, λ_max^ex, nm:	750
Cy7 extinction at λ_max^ex	199,000
Cy7 emission maximum, λ_max^fluor, nm:	773
Cy7 fluorescence quantum yield:	0.3
Quality control
NMR:	95+%
TLC:	pure
Functional testing (reaction with amine):	pass
Recommended protocols
NHS ester labeling of amino biomolecules	HTML \| PDF
Storage conditions
Store NHS esters at -20°C in the dark. Desiccate.

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