Cyanine5 amine
| Cat. # | Quantity | Price | Lead time | Buy this product |
|---|---|---|---|---|
| 130C0 | 1 mg | $125 | in stock | |
| 230C0 | 5 mg | $260 | in stock | |
| 430C0 | 25 mg |
$510
|
in stock | |
| 530C0 | 50 mg |
$895
|
in stock | |
| 630C0 | 100 mg |
$1490
|
in stock |
Cyanine5 amine is a reactive dye which contains amino group, an analog of Cy5® amine. This reagent can be coupled with a variety of activated esters and other electrophilic reagents. For example, this amine can be coupled with EDC-activated carboxylic groups.
This bright and photostable dye is suitable for many different methods of fluorescence detection. Colorful fluorophore can also be easily detected in small quantities (nanomols) by naked human eye.
Cyanine5 amine absorbance and emission spectra
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General properties
| Appearance: | dark blue powder |
| Molecular weight: | 653.77 |
| CAS number: | 1807529-70-9 |
| Molecular formula: | C38H54Cl2N4O |
| IUPAC name: | 3H-Indolium, 2-[5-[1-[6-[(6-aminohexyl)amino]-6-oxohexyl]-1,3-dihydro-3,3-dimethyl-2H-indol-2-ylidene]-1,3-pentadien-1-yl]-1,3,3-trimethyl- |
| Solubility: | moderate solubility in water, good in polar organic solvents (DMF, DMSO, alcohols) |
| Quality control: | NMR 1H, HPLC-MS (95%) |
| Storage conditions: | Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. |
| MSDS: | Download |
| Product specifications |
Spectral properties
| Excitation/absorption maximum, nm: | 646 |
| ε, L⋅mol−1⋅cm−1: | 250000 |
| Emission maximum, nm: | 662 |
| Fluorescence quantum yield: | 0.2 |
| CF260: | 0.03 |
| CF280: | 0.04 |
Product citations
- Mazrad, Z. A. I.; Refaat, A.; Morrow, J. P.; Voelcker, N. H.; Nicolazzo, J. A.; Leiske, M. N.; Kempe, K. Folic Acid-Conjugated Brush Polymers Show Enhanced Blood–Brain Barrier Crossing in Static and Dynamic In Vitro Models Toward Brain Cancer Targeting Therapy. ACS Biomater. Sci. Eng., 2024. doi: 10.1021/acsbiomaterials.3c01650
- Chau, Q.; Corado-Santiago, L.; Jones, S.; Dattelbaum, J.; Skromne, I. Physicochemical and Inflammatory Analysis of Unconjugated and Conjugated Bone-Binding Carbon Dots. ACS Omega, 2024, 9(1), 1320-1326. doi: 10.1021/acsomega.3c07653
- Yen, T.-Y.C.; Abbasi, A.Z.; He, C.; Lip, H.-Y.; Park, E.; Amini, M.A.; Adissu, H.A.; Foltz, W.; Rauth, A.M.; Henderson, J.; Wu, X.Y. Biocompatible and bioactivable terpolymer-lipid-MnO 2 Nanoparticle-based MRI contrast agent for improving tumor detection and delineation. Materials Today Bio, 2024, 25, 100954. doi: 10.1016/j.mtbio.2024.100954
- Martín-Asensio, A.; Dávila, S.; Cacheux, J.; Lindstaedt, A.; Dziadosz, A.; Witt, D.; Calero, M.; Balaz, I.; Rodríguez, I. Recapitulating Solid Stress on Tumor on a Chip for Nanomedicine Diffusive Transport Prediction. Advanced NanoBiomed Research, 2023, 3(6), 2200164. doi: 10.1002/anbr.202200164
Cy® is a trademark of GE Healthcare.
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